Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 New directions in liposome gene delivery.

Literature DB >> 10464771

New directions in liposome gene delivery.

Abstract

The history of liposomes, progress in liposome gene delivery, and future directions are discussed. Specific characteristics of liposomes and DNA:liposome complexes have been identified that are essential for optimal delivery and gene expression. Of particular interest are the requirements for increased delivery and high levels of gene expression in vivo. At present, significant efforts are focused towards achieving specific delivery and gene expression in target organs and tissues.

Mesh：

Substances：

Year: 1999 PMID： 10464771 DOI： 10.1007/bf02915810

Source DB: PubMed Journal: Mol Biotechnol ISSN： 1073-6085 Impact factor: 2.695

19 in total

1. Systemic gene expression after intravenous DNA delivery into adult mice.

Authors: N Zhu; D Liggitt; Y Liu; R Debs
Journal: Science Date: 1993-07-09 Impact factor: 47.728

2. In vivo gene delivery to the liver using reconstituted chylomicron remnants as a novel nonviral vector.

Authors: T Hara; Y Tan; L Huang
Journal: Proc Natl Acad Sci U S A Date: 1997-12-23 Impact factor: 11.205

3. Improved DNA: liposome complexes for increased systemic delivery and gene expression.

Authors: N S Templeton; D D Lasic; P M Frederik; H H Strey; D D Roberts; G N Pavlakis
Journal: Nat Biotechnol Date: 1997-07 Impact factor: 54.908

4. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung.

Authors: C J Wheeler; P L Felgner; Y J Tsai; J Marshall; L Sukhu; S G Doh; J Hartikka; J Nietupski; M Manthorpe; M Nichols; M Plewe; X Liang; J Norman; A Smith; S H Cheng
Journal: Proc Natl Acad Sci U S A Date: 1996-10-15 Impact factor: 11.205

5. In vitro and in vivo liposome-mediated gene transfer leads to human MDR1 expression in mouse bone marrow progenitor cells.

Authors: I Aksentijevich; I Pastan; Y Lunardi-Iskandar; R C Gallo; M M Gottesman; A R Thierry
Journal: Hum Gene Ther Date: 1996-06-10 Impact factor: 5.695

6. Gene transfer and expression in progeny after intravenous DNA injection into pregnant mice.

Authors: M Tsukamoto; T Ochiya; S Yoshida; T Sugimura; M Terada
Journal: Nat Genet Date: 1995-03 Impact factor: 38.330

7. In vivo gene delivery. Efficient transfection of T lymphocytes in adult mice.

Authors: R Philip; D Liggitt; M Philip; P Dazin; R Debs
Journal: J Biol Chem Date: 1993-08-05 Impact factor: 5.157

8. Time-dependent maturation of cationic liposome-DNA complex for serum resistance.

Authors: J P Yang; L Huang
Journal: Gene Ther Date: 1998-03 Impact factor: 5.250

9. A novel series of amphiphilic imidazolinium compounds for in vitro and in vivo gene delivery.

Authors: I Solodin; C S Brown; M S Bruno; C Y Chow; E H Jang; R J Debs; T D Heath
Journal: Biochemistry Date: 1995-10-17 Impact factor: 3.162

10. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice.

Authors: A R Thierry; Y Lunardi-Iskandar; J L Bryant; P Rabinovich; R C Gallo; L C Mahan
Journal: Proc Natl Acad Sci U S A Date: 1995-10-10 Impact factor: 11.205

12 in total

1. Capabilities of liposomes for topological transformation.

Authors: F Nomura; M Nagata; T Inaba; H Hiramatsu; H Hotani; K Takiguchi
Journal: Proc Natl Acad Sci U S A Date: 2001-02-20 Impact factor: 11.205

2. Analysis of novel nonviral gene transfer systems for gene delivery to cells of the musculoskeletal system.

Authors: Patrick Orth; Anja Weimer; Gunter Kaul; Dieter Kohn; Magali Cucchiarini; Henning Madry
Journal: Mol Biotechnol Date: 2007-10-17 Impact factor: 2.695

3. Electrostatic control of phospholipid polymorphism.

Authors: Y S Tarahovsky; A L Arsenault; R C MacDonald; T J McIntosh; R M Epand
Journal: Biophys J Date: 2000-12 Impact factor: 4.033

4. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma.

Authors: Arun K Iyer; Yang Su; Jinjin Feng; Xiaoli Lan; Xiaodong Zhu; Yue Liu; Dongwei Gao; Youngho Seo; Henry F Vanbrocklin; V Courtney Broaddus; Bin Liu; Jiang He
Journal: Biomaterials Date: 2011-01-20 Impact factor: 12.479

5. A functional chimaeric S-layer-enhanced green fluorescent protein to follow the uptake of S-layer-coated liposomes into eukaryotic cells.

Authors: Nicola Ilk; Seta Küpcü; Gerald Moncayo; Sigrid Klimt; Rupert C Ecker; Renate Hofer-Warbinek; Eva M Egelseer; Uwe B Sleytr; Margit Sára
Journal: Biochem J Date: 2004-04-15 Impact factor: 3.857

6. Optimization of Non-Viral Gene Therapeutics Using Bilamellar Invaginated Vesicles.

Authors: Nancy Smyth Templeton; Neil Senzer
Journal: J Genet Syndr Gene Ther Date: 2011-12-17

Review 7. Nonviral delivery for genomic therapy of cancer.

Authors: Nancy Smyth Templeton
Journal: World J Surg Date: 2009-04 Impact factor: 3.352

8. Aerosol delivery of kinase-deficient Akt1 attenuates Clara cell injury induced by naphthalene in the lungs of dual luciferase mice.

Authors: Arash Minai-Tehrani; Young-Chan Park; Soon-Kyung Hwang; Jung-Taek Kwon; Seung-Hee Chang; Sung-Jin Park; Kyeong-Nam Yu; Ji-Eun Kim; Ji-Young Shin; Ji-Hye Kim; Bitna Kang; Seong-Ho Hong; Myung-Haing Cho
Journal: J Vet Sci Date: 2011-12 Impact factor: 1.672

9. Reversible masking using low-molecular-weight neutral lipids to achieve optimal-targeted delivery.

Authors: Nancy Smyth Templeton; Neil Senzer
Journal: J Drug Deliv Date: 2012-05-10

10. Safety and in vivo expression of a GNE-transgene: a novel treatment approach for hereditary inclusion body myopathy-2.

Authors: Anagha P Phadke; Chris Jay; Salina J Chen; Courtney Haddock; Zhaohui Wang; Yang Yu; Derek Nemunaitis; Gregory Nemunaitis; Nancy S Templeton; Neil Senzer; Phillip B Maples; Alex W Tong; John Nemunaitis
Journal: Gene Regul Syst Bio Date: 2009-05-08