Gene Therapy Monitoring: Clinical Monitoring for Efficacy and Potential Toxicity.

Since the first human clinical trial was initiated in 1990, the field of gene therapy has gone through a period explosive growth. Building on a sound foundation of many years of basic and clinical research this novel therapeutic approach has the potential to revolutionize medicine. As gene therapy moves from a research setting, however, clinical monitoring for efficacy and potential toxicity will become increasingly important, perhaps becoming as commonplace as therapeutic drug monitoring is today.