Literature DB >> 10462151

The persistence of mood disorders following traumatic brain injury: a 1 year follow-up.

A Bowen1, M A Chamberlain, A Tennant, V Neumann, M Conner.   

Abstract

The study investigated whether the frequency of mood disorders following traumatic brain injury (TBI) increased with time. Consecutive hospital admissions completed the Wimbledon Self-Report Scale at 6 and 12 months post-injury. Scores in the 'borderline/case' range were deemed clinically significant. Seventy-seven of those assessed at 6 months completed the 12 month follow-up. Those lost to follow-up (22) were not more likely to have been classified 'borderline/case' at 6 months. They were more likely to have been 'unoccupied' pre-injury (p=0.002). The frequency of clinically significant disorders did not change significantly, being 39% at 6 months and 35% 1 year post-injury. The majority of subjects (58) maintained the same clinical classification at both assessments. Eight of the 47 (17%) classified 'normal' at 6 months changed to 'borderline/case' at 12 months. However, 11 of the 30 (37%) classified 'borderline/case' at 6 months were 'normal' at 12 months. The direction of change was not statistically significant (p=0.5). These findings are consistent with previous research. However, the present study examined a larger sample and included a wider range of injury severity, thereby increasing the generalizability of the findings. Also, a broader spectrum of mood disorders was investigated which adds to previous work specifically on depression.

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Year:  1999        PMID: 10462151     DOI: 10.1080/026990599121449

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  3 in total

1.  Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice.

Authors:  Xiaodi Han; Jing Tong; Jun Zhang; Arash Farahvar; Ernest Wang; Jiankai Yang; Uzma Samadani; Douglas H Smith; Jason H Huang
Journal:  J Neurotrauma       Date:  2011-05-12       Impact factor: 5.269

Review 2.  Common psychiatric syndromes and pharmacologic treatments of traumatic brain injury.

Authors:  L A Labbate; D L Warden
Journal:  Curr Psychiatry Rep       Date:  2000-06       Impact factor: 5.285

3.  Self-perceived health status following aneurysmal subarachnoid haemorrhage: a cohort study.

Authors:  Audrey C Quinn; Deepti Bhargava; Yahia Z Al-Tamimi; Matthew J Clark; Stuart A Ross; Alan Tennant
Journal:  BMJ Open       Date:  2014-04-03       Impact factor: 2.692

  3 in total

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