Literature DB >> 10461190

Putting a new twist on actin: ADF/cofilins modulate actin dynamics.

J R Bamburg1, A McGough, S Ono.   

Abstract

The actin-depolymerizing factor (ADF)/cofilins are a family of essential actin regulatory proteins, ubiquitous among eukaryotes, that enhance the turnover of actin by regulating the rate constants of polymerization and depolymerization at filament ends, changing the twist of the filament and severing actin filaments. Genetic and cell-biological studies have shown that an ADF/cofilin is required to drive the high turnover of the actin cytoskeleton observed in vivo. The activity of ADF/cofilin is regulated by a variety of mechanisms, including specific phosphorylation and dephosphorylation. This review addresses aspects of ADF/cofilin structure, dynamics, regulation and function.

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Year:  1999        PMID： 10461190     DOI： 10.1016/s0962-8924(99)01619-0

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  128 in total

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Review 3.  Actin and actin-binding proteins in higher plants.

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Journal:  Plant Cell       Date:  2003-01       Impact factor: 11.277

6.  Biological role and structural mechanism of twinfilin-capping protein interaction.

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7.  Genetic dissection of meiotic cytokinesis in Drosophila males.

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Journal:  Mol Biol Cell       Date:  2004-03-05       Impact factor: 4.138

8.  Actin depolymerizing factors ADF7 and ADF10 play distinct roles during pollen development and pollen tube growth.

Authors:  Firas Bou Daher; Anja Geitmann
Journal:  Plant Signal Behav       Date:  2012-07-01

9.  Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I.

Authors:  Dale A Fortin; Monika A Davare; Taasin Srivastava; James D Brady; Sean Nygaard; Victor A Derkach; Thomas R Soderling
Journal:  J Neurosci       Date:  2010-09-01       Impact factor: 6.167

10.  Simulation of cell motility that reproduces the force-velocity relationship.

Authors:  Christian H Schreiber; Murray Stewart; Thomas Duke
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-03       Impact factor: 11.205
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