Literature DB >> 10461151

Microdispensing technologies in drug discovery.

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Abstract

Because of the advent of managed care,the pharmaceutical industry is entering a new era, characterized by increased competition and pricing pressures. As a result, drug discovery within pharmaceutical companies is rapidly embracing new paradigms to help bring more novel drugs to the market as rapidly as possible. One paradigm currently being pursued is the miniaturization of the processes involved in the exploratory phase of drug discovery. This reduction in scale has led to the development of new dispensing technologies. This review examines several microdispensing technologies for drug discovery.

Year:  1999        PMID: 10461151     DOI: 10.1016/s1359-6446(99)01388-4

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  9 in total

1.  Multi-dimensional studies of synthetic genetic promoters enabled by microfluidic impact printing.

Authors:  Jinzhen Fan; Fernando Villarreal; Brent Weyers; Yunfeng Ding; Kuo Hao Tseng; Jiannan Li; Baoqing Li; Cheemeng Tan; Tingrui Pan
Journal:  Lab Chip       Date:  2017-06-27       Impact factor: 6.799

2.  A simple and effective calibration method to determine the accuracy of liquid-handling nano-dispenser devices.

Authors:  Sonia Rodríguez-Puente; Judith Linacero-Blanco; Alicia Guasch
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2013-02-23

Review 3.  Current Trends on Medical and Pharmaceutical Applications of Inkjet Printing Technology.

Authors:  Nicolaos Scoutaris; Steven Ross; Dennis Douroumis
Journal:  Pharm Res       Date:  2016-05-12       Impact factor: 4.200

Review 4.  Controlling mass transport in microfluidic devices.

Authors:  Jason S Kuo; Daniel T Chiu
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2011       Impact factor: 10.745

5.  Self-digitization of sample volumes.

Authors:  Dawn E Cohen; Thomas Schneider; Michelle Wang; Daniel T Chiu
Journal:  Anal Chem       Date:  2010-07-01       Impact factor: 6.986

6.  Automated Gravimetric Calibration to Optimize the Accuracy and Precision of TECAN Freedom EVO Liquid Handler.

Authors:  Laurent Bessemans; Vanessa Jully; Caroline de Raikem; Mathieu Albanese; Nicolas Moniotte; Pascal Silversmet; Dominique Lemoine
Journal:  J Lab Autom       Date:  2016-02-23

7.  Nanoliter-scale protein crystallization and screening with a microfluidic droplet robot.

Authors:  Ying Zhu; Li-Na Zhu; Rui Guo; Heng-Jun Cui; Sheng Ye; Qun Fang
Journal:  Sci Rep       Date:  2014-05-23       Impact factor: 4.379

8.  Nanolitre-scale crystallization using acoustic liquid-transfer technology.

Authors:  Armando G Villaseñor; April Wong; Ada Shao; Ankur Garg; Timothy J Donohue; Andreas Kuglstatter; Seth F Harris
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2012-07-17

Review 9.  Automated analytical microarrays: a critical review.

Authors:  Michael Seidel; Reinhard Niessner
Journal:  Anal Bioanal Chem       Date:  2008-05-27       Impact factor: 4.142

  9 in total

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