Literature DB >> 10460772

Diabetic versus non-diabetic colour vision after cataract surgery.

L Kessel1, A Alsing, M Larsen.   

Abstract

AIMS: To examine whether the colour vision abnormalities found in phakic patients with diabetes mellitus is preserved after removal of the lens by cataract surgery.
METHODS: 21 diabetic (16 IDDM and five NIDDM) and 19 non-diabetic patients of comparable age, postoperative visual acuity, and sex distribution, all aphakic or pseudophakic following cataract surgery, had their monocular colour vision examined using the Farnsworth-Munsell 100 hue test. The fundus status of the diabetic patients ranged from no retinopathy to photocoagulation treated proliferative diabetic retinopathy. Patients with macular oedema were specifically excluded from the study.
RESULTS: The error scores of both the diabetic (mean 146 (SD 94)) and the non-diabetic patients (83 (79)) did not deviate significantly from the age related normal range. The error score in the diabetic group was significantly higher than in the non-diabetic group (p=0.02) but the amplitude of the difference was small in comparison with previous studies of phakic subjects. The error scores in the diabetic group were not correlated with the degree of retinopathy (p>0.2).
CONCLUSION: After cataract surgery only a minor difference exists between the colour vision scores of diabetic and non-diabetic patients. This indicates that accelerated yellowing of the lens in diabetes is the predominant cause of the colour vision anomaly found in phakic diabetic patients.

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Year:  1999        PMID: 10460772      PMCID: PMC1723195          DOI: 10.1136/bjo.83.9.1042

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  14 in total

1.  [A case of diabetic color blindness].

Authors:  A DUBOIS-POULSEN; P COCHET
Journal:  Bull Soc Ophtalmol Fr       Date:  1954-05

2.  The diabetic eye and colour vision.

Authors:  P R Kinnear; P A Aspinall; R Lakowski
Journal:  Trans Ophthalmol Soc U K       Date:  1972

3.  Lens autofluorescence in diabetes compared with the level of glycosylated hemoglobin A1c.

Authors:  B Kjer; M Larsen; I Bendtson; C Binder; P Dalgaard; H Lund-Andersen
Journal:  Acta Ophthalmol Suppl       Date:  1987

4.  A new assessment of the normal ranges of the Farnsworth-Munsell 100-hue test scores.

Authors:  G Verriest; J Van Laethem; A Uvijls
Journal:  Am J Ophthalmol       Date:  1982-05       Impact factor: 5.258

5.  The relationship between hue discrimination and contrast sensitivity deficits in patients with diabetes mellitus.

Authors:  G L Trick; R M Burde; M O Gordon; J V Santiago; C Kilo
Journal:  Ophthalmology       Date:  1988-05       Impact factor: 12.079

6.  Prediction of diabetic retinopathy from clinical variables and color vision data.

Authors:  P A Aspinall; P R Kinnear; L J Duncan; B F Clarke
Journal:  Diabetes Care       Date:  1983 Mar-Apr       Impact factor: 19.112

7.  Accelerated age-related browning of human collagen in diabetes mellitus.

Authors:  V M Monnier; R R Kohn; A Cerami
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

8.  Diabetic cataract formation: potential role of glycosylation of lens crystallins.

Authors:  V J Stevens; C A Rouzer; V M Monnier; A Cerami
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

9.  Autofluorescence of the lens in diabetic and healthy subjects by fluorophotometry.

Authors:  J C Bleeker; J A van Best; L Vrij; E A van der Velde; J A Oosterhuis
Journal:  Invest Ophthalmol Vis Sci       Date:  1986-05       Impact factor: 4.799

10.  Retinopathy and retinal function in insulin-dependent diabetes mellitus.

Authors:  J Moloney; M I Drury
Journal:  Br J Ophthalmol       Date:  1982-12       Impact factor: 4.638

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  4 in total

1.  Extent of foveal tritanopia in diabetes mellitus.

Authors:  N Davies; A Morland
Journal:  Br J Ophthalmol       Date:  2003-06       Impact factor: 4.638

2.  Impairment of Colour Vision in Diabetes with No Retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SNDREAMS- II, Report 3).

Authors:  Laxmi Gella; Rajiv Raman; Vaitheeswaran Kulothungan; Swakshyar Saumya Pal; Suganeswari Ganesan; Tarun Sharma
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240

3.  Inhibition of Stat3 by a Small Molecule Inhibitor Slows Vision Loss in a Rat Model of Diabetic Retinopathy.

Authors:  Phillip A Vanlandingham; Didier J Nuno; Alexander B Quiambao; Eric Phelps; Ronald A Wassel; Jian-Xing Ma; Krysten M Farjo; Rafal A Farjo
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-04-01       Impact factor: 4.799

4.  Tryptophan and Non-Tryptophan Fluorescence of the Eye Lens Proteins Provides Diagnostics of Cataract at the Molecular Level.

Authors:  Anna Gakamsky; Rory R Duncan; Nicola M Howarth; Baljean Dhillon; Kim K Buttenschön; Daniel J Daly; Dmitry Gakamsky
Journal:  Sci Rep       Date:  2017-01-10       Impact factor: 4.379

  4 in total

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