Literature DB >> 10459329

Sickle cell disease of the spine in children.

E Roger1, M Letts.   

Abstract

OBJECTIVE: To determine the incidence of back pain in children admitted with sickle cell disease so as to increase awareness of this disease in black children presenting with back pain or discomfort.
DESIGN: A retrospective review.
SETTING: The Children's Hospital of Eastern Ontario in Ottawa, a tertiary care, university affiliated centre. PATIENTS: Thirty children were treated for active sickle cell disease between 1990 and 1996. Eleven (5 boys, 6 girls) suffered vascular-occlusive phenomena occurring in bone, referred to as "bony crises," requiring a total of 49 admissions. MAIN OUTCOME MEASURES: Clinical manifestations of spinal involvement by sickle cell disease. MAIN
RESULTS: The spine represented the second most common area of bone involvement (26%) exceeded only by the knee (35%). The vertebral level affected was lumbosacral in 66% of cases, followed by thoracic in 22% and cervical in only 12%. Eighty-six percent of the children with spinal pain were anemic upon presentation, 71% had an elevated leukocyte count, 15% were hyponatremic and 15% were hyperkalemic. Minimal physical signs in the spine were noted, other than a local tenderness over the spinous process in 71% and a decreased range of back motion in 17%.
CONCLUSIONS: Sickle cell disease is becoming more common in Canada as a result of increasing immigration from African countries and should always be considered as a possible cause of back pain in a black child.

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Mesh:

Year:  1999        PMID: 10459329      PMCID: PMC3788999     

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  2 in total

1.  Meningeal signs and facial edema in a child with sickle cell disease.

Authors:  Marie Gauthier; Rochelle Winikoff
Journal:  CMAJ       Date:  2010-05-10       Impact factor: 8.262

Review 2.  Review of Sickle Cell Disease and Spinal Pathology.

Authors:  Hayeem L Rudy; David Yang; Andrew D Nam; Woojin Cho
Journal:  Global Spine J       Date:  2018-09-17
  2 in total

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