Literature DB >> 10459027

Selective uterine artery embolization as primary treatment for symptomatic leiomyomata uteri.

F L Hutchins1, R Worthington-Kirsch, R P Berkowitz.   

Abstract

STUDY
OBJECTIVE: To analyze initial experience with uterine artery embolization for treatment of symptomatic leiomyomata.
DESIGN: Prospective, longitudinal study (Canadian Task Force classification II-2).
SETTING: Private practice, university-affiliated hospital. PATIENTS: Three hundred five women (age 26-52 yrs).
INTERVENTIONS: Uterine artery embolization, performed over 2 years by a single radiologist working in collaboration with a single gynecology practice.
MEASUREMENTS AND MAIN RESULTS: Embolization was technically successful in 96% of patients. No major complications occurred. Average reduction in uterine volume was 48%. Control of menorrhagia was reported by 86% of patients at 3 months, 85% at 6 months, and 92% at 12 months after the procedure. Bulk symptoms were satisfactorily controlled in 64% of patients at 3 months, 77% at 6 months, and 92% at 12 months. Six women subsequently underwent hysterectomy and five had myomectomy.
CONCLUSION: Uterine artery embolization appears to be a highly effective treatment for symptomatic uterine leiomyomata. Its impact on fertility and pregnancy remain to be investigated fully. (J Am Assoc Gynecol Laparosc 6(3):279-284, 1999)

Entities:  

Mesh:

Year:  1999        PMID: 10459027     DOI: 10.1016/s1074-3804(99)80061-9

Source DB:  PubMed          Journal:  J Am Assoc Gynecol Laparosc        ISSN: 1074-3804


  14 in total

1.  Uterine artery embolization: state of the art.

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Review 3.  Current evidence on uterine embolization for fibroids.

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Review 6.  Uterine fibroid embolization: CME update for family physicians.

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Review 9.  [Technique and methods in uterine leiomyoma embolization].

Authors:  T K Helmberger; T F Jakobs; M F Reiser
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10.  Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model.

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