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Literature DB >> 10458989

Adhesins in Candida albicans.

Abstract

The adherent properties of Candida albicans blastoconidia and germ tubes have long been appreciated, but little is known about the mechanisms responsible for adherence. Recently, three genes, ALA1, ALS1 and HWP1, encoding proteins with adherent properties and motifs consistent with linkage to the beta-1, 6-glucan of C. albicans cell walls have provided insight into the topology of protein adhesins. Hwp1, a developmentally regulated adhesin of germ tubes and hyphae, attaches to buccal epithelial cells by an unconventional, transglutaminase-mediated mechanism of adhesion.

Entities: Chemical Disease Species

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Year: 1999 PMID： 10458989 DOI： 10.1016/S1369-5274(99)80062-9

Source DB: PubMed Journal: Curr Opin Microbiol ISSN： 1369-5274 Impact factor: 7.934

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Cited

39 in total

1. Maintenance of mating cell integrity requires the adhesin Fig2p.

Authors: Mingliang Zhang; Daniel Bennett; Scott E Erdman
Journal: Eukaryot Cell Date: 2002-10

2. A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating.

Authors: B Guo; C A Styles; Q Feng; G R Fink
Journal: Proc Natl Acad Sci U S A Date: 2000-10-24 Impact factor: 11.205

3. A parasitic phase-specific adhesin of Coccidioides immitis contributes to the virulence of this respiratory Fungal pathogen.

Authors: Chiung-Yu Hung; Jieh-Juen Yu; Kalpathi R Seshan; Utz Reichard; Garry T Cole
Journal: Infect Immun Date: 2002-07 Impact factor: 3.441

4. The Opi1p transcription factor affects expression of FLO11, mat formation, and invasive growth in Saccharomyces cerevisiae.

Authors: Todd B Reynolds
Journal: Eukaryot Cell Date: 2006-08

5. Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

Authors: Alexandra Correia; Ulrich Lermann; Luzia Teixeira; Filipe Cerca; Sofia Botelho; Rui M Gil da Costa; Paula Sampaio; Fátima Gärtner; Joachim Morschhäuser; Manuel Vilanova; Célia Pais
Journal: Infect Immun Date: 2010-08-02 Impact factor: 3.441

10. The adhesin Hwp1 and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating.

Authors: Karla J Daniels; Shawn R Lockhart; Janet F Staab; Paula Sundstrom; David R Soll
Journal: Mol Biol Cell Date: 2003-10-17 Impact factor: 4.138

Adhesins in Candida albicans.

1. Maintenance of mating cell integrity requires the adhesin Fig2p.

2. A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating.

3. A parasitic phase-specific adhesin of Coccidioides immitis contributes to the virulence of this respiratory Fungal pathogen.

4. The Opi1p transcription factor affects expression of FLO11, mat formation, and invasive growth in Saccharomyces cerevisiae.

5. Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

6. Conserved WCPL and CX4C domains mediate several mating adhesin interactions in Saccharomyces cerevisiae.

7. Posttranslational modifications required for cell surface localization and function of the fungal adhesin Aga1p.

8. Expression of plasma coagulase among pathogenic Candida species.

9. EAP1, a Candida albicans gene involved in binding human epithelial cells.

10. The adhesin Hwp1 and the first daughter cell localize to the a/a portion of the conjugation bridge during Candida albicans mating.