Literature DB >> 10458277

Biphasic calcium phosphate/hydrosoluble polymer composites: a new concept for bone and dental substitution biomaterials.

G Daculsi1, P Weiss, J M Bouler, O Gauthier, F Millot, E Aguado.   

Abstract

Calcium phosphate materials have been increasingly employed in orthopedic and dental applications in recent years and are now being developed for use in noninvasive surgery or as carriers for drug delivery systems. We developed an injectable bone substitute (IBS) constituted of biphasic calcium phosphate and a hydrosoluble polymer as a carrier. In vivo biocompatibility and biofunctionality of IBS were tested in rabbits using implants in osseous and nonosseous areas. The results obtained demonstrated that the concept of IBS, a filler without initial mechanical properties but able to be rapidly resorbed and replaced by newly formed bone, can be applied to new surgical applications in orthopedic surgery, maxillofacial surgery, and dentistry for pulp capping and root filling.

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Year:  1999        PMID： 10458277     DOI： 10.1016/s8756-3282(99)00135-0

Source DB:  PubMed          Journal:  Bone        ISSN： 1873-2763            Impact factor:   4.398


  20 in total

1.  Setting solution concentration effect on properties of a TTCP/DCPA-derived calcium phosphate cement.

Authors:  Chang-Keng Chen; Chien-Ping Ju; Jiin-Huey Chern Lin
Journal:  J Mater Sci Mater Med       Date:  2012-06-12       Impact factor: 3.896

2.  Development of bisphosphonates controlled delivery systems for bone implantation: influence of the formulation and process used on in vitro release.

Authors:  A Billon-Chabaud; A Gouyette; C Merle; J M Bouler
Journal:  J Mater Sci Mater Med       Date:  2010-02-23       Impact factor: 3.896

3.  In vitro characterisation of calcium phosphate biomaterials loaded with lidocaine hydrochloride and morphine hydrochloride.

Authors:  H Gautier; V Chamblain; P Weiss; C Merle; J M Bouler
Journal:  J Mater Sci Mater Med       Date:  2010-11-03       Impact factor: 3.896

4.  Three-year results following regenerative periodontal surgery of advanced intrabony defects with enamel matrix derivative alone or combined with a synthetic bone graft.

Authors:  Thomas Hoffmann; Elyan Al-Machot; Jörg Meyle; Pia-Merete Jervøe-Storm; Søren Jepsen
Journal:  Clin Oral Investig       Date:  2015-07-15       Impact factor: 3.573

Review 5.  Biocomposites and hybrid biomaterials based on calcium orthophosphates.

Authors:  Sergey V Dorozhkin
Journal:  Biomatter       Date:  2011 Jul-Sep

6.  Interaction between hydroxypropyl methylcellulose and biphasic calcium phosphate after steam sterilisation: capillary gas chromatography studies.

Authors:  X Bourges; M Schmitt; Y Amouriq; G Daculsi; G Legeay; P Weiss
Journal:  J Biomater Sci Polym Ed       Date:  2001       Impact factor: 3.517

7.  Hydrogels That Allow and Facilitate Bone Repair, Remodeling, and Regeneration.

Authors:  Aaron R Short; Deepthi Koralla; Ameya Deshmukh; Benjamin Wissel; Benjamin Stocker; Mark Calhoun; David Dean; Jessica O Winter
Journal:  J Mater Chem B       Date:  2015-09-03       Impact factor: 6.331

8.  Developments in injectable multiphasic biomaterials. The performance of microporous biphasic calcium phosphate granules and hydrogels.

Authors:  G Daculsi; A P Uzel; P Weiss; E Goyenvalle; E Aguado
Journal:  J Mater Sci Mater Med       Date:  2009-11-01       Impact factor: 3.896

9.  Skin sensitization study of two hydroxypropyl methylcellulose components (Benecel and E4M) of an injectable bone substitute in guinea pigs.

Authors:  Y Amouriq; X Bourges; P Weiss; J Bosco; J-M Bouler; G Daculsi
Journal:  J Mater Sci Mater Med       Date:  2002-02       Impact factor: 3.896

10.  Current state of the art of biphasic calcium phosphate bioceramics.

Authors:  Guy Daculsi; Olivier Laboux; Olivier Malard; Pierre Weiss
Journal:  J Mater Sci Mater Med       Date:  2003-03       Impact factor: 3.896
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