Literature DB >> 10454900

In vitro anti-Helicobacter pylori activity of some flavonoids and their metabolites.

E A Bae, M J Han, D H Kim.   

Abstract

The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC was 10-20 micrograms/ml. However, these active compounds against HP did nearly not inhibit the urease activity of HP.

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Year:  1999        PMID： 10454900     DOI： 10.1055/s-2006-960805

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  21 in total

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