Literature DB >> 10454788

Severe hypertensive sequelae in a child with Seckel syndrome (bird-like dwarfism).

J M Sorof1, C Dow-Smith, P J Moore.   

Abstract

We report a 19-year-old male with Seckel syndrome (bird-like dwarfism) who presents with malignant hypertension associated with hypertensive nephrosclerosis, dilated cardiomyopathy, and a ruptured cerebral artery aneurysm. Although end-organ injury due to chronic hypertension occurs frequently in adults, no previous reports of renal insufficiency due to hypertension exist in children or adolescents. We speculate that this patient may have been particularly prone to hypertensive end-organ injury due to his extreme short stature.

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Year:  1999        PMID: 10454788     DOI: 10.1007/s004670050623

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN: 0931-041X            Impact factor:   3.714


  6 in total

1.  Microcephalic osteodysplastic primordial dwarfism type II is associated with global vascular disease.

Authors:  Angela L Duker; Dagmar Kinderman; Christy Jordan; Tim Niiler; Carissa M Baker-Smith; Louise Thompson; David A Parry; Ricki S Carroll; Michael B Bober
Journal:  Orphanet J Rare Dis       Date:  2021-05-20       Impact factor: 4.123

2.  Moyamoya-like vasculopathy and Seckel syndrome: just a coincidence?

Authors:  Ralph Rahme; Louis Crevier; Josée Dubois; Claude Mercier
Journal:  Childs Nerv Syst       Date:  2010-07       Impact factor: 1.475

Review 3.  Malignant hypertension and cerebral haemorrhage in Seckel syndrome.

Authors:  Rossella Di Bartolomeo; Giancarlo Polidori; Marco Piastra; Luigi Viola; Guiseppe Zampino; Antonio Chiaretti
Journal:  Eur J Pediatr       Date:  2003-10-15       Impact factor: 3.183

4.  Clinical and functional characterization of a patient carrying a compound heterozygous pericentrin mutation and a heterozygous IGF1 receptor mutation.

Authors:  Eva Müller; Desiree Dunstheimer; Jürgen Klammt; Daniela Friebe; Wieland Kiess; Jürgen Kratzsch; Tassilo Kruis; Sandy Laue; Roland Pfäffle; Tillmann Wallborn; Peter H Heidemann
Journal:  PLoS One       Date:  2012-05-31       Impact factor: 3.240

5.  A Child with Seckel Syndrome and Arterial Stenosis: Case Report and Literature Review.

Authors:  Minoo Saeidi; Morteza Shahbandari
Journal:  Int Med Case Rep J       Date:  2020-05-14

6.  Central nervous system vasculopathy and Seckel syndrome: case illustration and systematic review.

Authors:  Osama Khojah; Saeed Alamoudi; Nouf Aldawsari; Mohammed Babgi; Ahmed Lary
Journal:  Childs Nerv Syst       Date:  2021-08-03       Impact factor: 1.475

  6 in total

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