Literature DB >> 10453400

BMIPP imaging to assess functional outcome in patients with acute and chronic left ventricular dysfunction.

P R Franken1, A S Hambÿe, F W De Geeter.   

Abstract

Assessment of myocardial viability is an important clinical issue for patient management during the acute and chronic stages of myocardial infarction. BMIPP (15-(p-iodophenyl)-3-(R,S)-methyl pentadecanoic acid) is a free fatty acid analogue which is trapped in the myocardium, thus permitting for metabolic imaging with single photon emission computerized tomography (SPECT). Less BMIPP than flow tracers that may be observed in the areas of infarction, may reflect the metabolic shift from fatty acid to glucose utilization in ischaemic myocardium. In this sense, the combined imaging of BMIPP and a flow tracer with SPECT may provide similar and important information as fluoro-18 deoxyglucose (FDG) and positron emission tomography (PET) regarding the assessment of myocardial viability. The purpose of this article is to review the clinical impact of BMIPP in patients with acute and with chronic left ventricular dysfunction for the identification of jeopardized but viable myocardium and the prediction of the functional outcome.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10453400     DOI： 10.1023/a:1006128116056

Source DB:  PubMed          Journal:  Int J Card Imaging        ISSN： 0167-9899


  27 in total

1.  Myocardial accumulation of iodinated beta-methyl-branched fatty acid analogue, iodine-125-15-(p-iodophenyl)-3-(R,S)methylpentadecanoic acid (BMIPP), in relation to ATP concentration.

Authors:  Y Fujibayashi; Y Yonekura; Y Takemura; K Wada; K Matsumoto; N Tamaki; K Yamamoto; J Konishi; A Yokoyama
Journal:  J Nucl Med       Date:  1990-11       Impact factor: 10.057

2.  Regional metabolic abnormality in relation to perfusion and wall motion in patients with myocardial infarction: assessment with emission tomography using an iodinated branched fatty acid analog.

Authors:  N Tamaki; M Kawamoto; Y Yonekura; Y Fujibayashi; N Takahashi; J Konishi; R Nohara; H Kambara; C Kawai; K Ikekubo
Journal:  J Nucl Med       Date:  1992-05       Impact factor: 10.057

3.  Recovery of impaired left ventricular function in patients with acute myocardial infarction is predicted by the discordance in defect size on 123I-BMIPP and 201Tl SPET images.

Authors:  T Ito; J Tanouchi; J Kato; T Morioka; M Nishino; K Iwai; H Tanahashi; Y Yamada; M Hori; T Kamada
Journal:  Eur J Nucl Med       Date:  1996-08

4.  Metabolic fate of iodine-123-BMIPP in canine myocardium after administration of etomoxir.

Authors:  R Hosokawa; R Nohara; Y Fujibayashi; K Okuda; M Ogino; T Hata; M Fujita; N Tamaki; J Konishi; S Sasayama
Journal:  J Nucl Med       Date:  1996-11       Impact factor: 10.057

5.  Clinical results with beta-methyl-p-(123I)iodophenylpentadecanoic acid, single-photon emission computed tomography in cardiac disease.

Authors:  T Nishimura; T Uehara; T Shimonagata; S Nagata; K Haze
Journal:  J Nucl Cardiol       Date:  1994 Mar-Apr       Impact factor: 5.952

6.  Abnormal BMIPP uptake in chronically dysfunctional myocardial segments: correlation with contractile response to low-dose dobutamine.

Authors:  A S Hambÿe; M M Vaerenberg; A A Dobbeleir; P A Van den Heuvel; P R Franken
Journal:  J Nucl Med       Date:  1998-11       Impact factor: 10.057

7.  Effect of glucose and insulin infusion on the myocardial extraction of a radioiodinated methyl-substituted fatty acid.

Authors:  J A Bianco; D R Elmaleh; J A Leppo; M A King; A Moring; E Livni; E Espinoza; J S Alpert; H W Strauss
Journal:  Eur J Nucl Med       Date:  1986

8.  Significance of defect severity in technetium-99m-MIBI SPECT at rest to assess myocardial viability: comparison with fluorine-18-FDG PET.

Authors:  C Altehoefer; J vom Dahl; M Biedermann; R Uebis; I Beilin; F Sheehan; P Hanrath; U Buell
Journal:  J Nucl Med       Date:  1994-04       Impact factor: 10.057

9.  Prognostic value of iodine-123 labelled BMIPP fatty acid analogue imaging in patients with myocardial infarction.

Authors:  N Tamaki; E Tadamura; T Kudoh; N Hattori; Y Yonekura; R Nohara; S Sasayama; K Ikekubo; H Kato; J Konishi
Journal:  Eur J Nucl Med       Date:  1996-03

10.  Relationship between blood flow and fatty acid metabolism in subacute myocardial infarction: a study by means of 99mTc-Sestamibi and 123I-beta-methyl-iodo-phenyl pentadecanoic acid.

Authors:  F De Geeter; P R Franken; F F Knapp; A Bossuyt
Journal:  Eur J Nucl Med       Date:  1994-04
View more
  2 in total

1.  Is BMIPP a sensitive marker for myocardial ischaemic stress? Against.

Authors:  Robert J Gropler
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-05-27       Impact factor: 9.236

Review 2.  Multimodality imaging for assessment of myocardial viability: nuclear, echocardiography, MR, and CT.

Authors:  James A Arrighi; Vasken Dilsizian
Journal:  Curr Cardiol Rep       Date:  2012-04       Impact factor: 2.931
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.