OBJECTIVE: To determine the prevalence of zygapophyseal (ZA) joint ankylosis in ankylosing spondylitis (AS) and the relation of this ankylosis to the presence of bridging syndesmophytes. METHODS: Roentgenograms of the cervical and lumbar spine of 50 patients with AS were scored by a vertebral body score according to Taylor and a newly developed score for ZA joint involvement. RESULTS: At the cervical level 22% of the ZA joints were ankylosed and 16% of the levels presented bridging syndesmophytes. In the lumbar spine 22% of ZA joints were ankylosed and 16% of the vertebral levels showed ankylosis in both ZA joints. Bridging syndesmophytes were present in 11% of the vertebral levels. Ankylosis of the ZA joints and bridging syndesmophytes were seen simultaneously in 14% of the cervical levels and in 9% of all lumbar levels. Ankylosed ZA joints were present in 21% of the lumbar levels without bridging syndesmophytes and in 8% of the cervical levels without bridging syndesmophytes. Bridging syndesmophytes at a given level without ankylosis of the respective ZA joint were uncommon: 4 of 201 lumbar levels and 4 of 238 cervical levels. Ankylosis of the ZA joint and presence of bridging syndesmophytes is markedly associated, but in a discordant way. CONCLUSION: The ZA joint is affected in a major way in AS. Involvement of the ZA joint and the presence of syndesmophytes are related. An asymmetric relation suggests that the ZA joint is primarily involved in AS.
OBJECTIVE: To determine the prevalence of zygapophyseal (ZA) joint ankylosis in ankylosing spondylitis (AS) and the relation of this ankylosis to the presence of bridging syndesmophytes. METHODS: Roentgenograms of the cervical and lumbar spine of 50 patients with AS were scored by a vertebral body score according to Taylor and a newly developed score for ZA joint involvement. RESULTS: At the cervical level 22% of the ZA joints were ankylosed and 16% of the levels presented bridging syndesmophytes. In the lumbar spine 22% of ZA joints were ankylosed and 16% of the vertebral levels showed ankylosis in both ZA joints. Bridging syndesmophytes were present in 11% of the vertebral levels. Ankylosis of the ZA joints and bridging syndesmophytes were seen simultaneously in 14% of the cervical levels and in 9% of all lumbar levels. Ankylosed ZA joints were present in 21% of the lumbar levels without bridging syndesmophytes and in 8% of the cervical levels without bridging syndesmophytes. Bridging syndesmophytes at a given level without ankylosis of the respective ZA joint were uncommon: 4 of 201 lumbar levels and 4 of 238 cervical levels. Ankylosis of the ZA joint and presence of bridging syndesmophytes is markedly associated, but in a discordant way. CONCLUSION: The ZA joint is affected in a major way in AS. Involvement of the ZA joint and the presence of syndesmophytes are related. An asymmetric relation suggests that the ZA joint is primarily involved in AS.
Authors: J Braun; D van der Heijde; M Dougados; P Emery; M A Khan; J Sieper; Sj van der Linden Journal: Ann Rheum Dis Date: 2002-12 Impact factor: 19.103
Authors: Michael M Ward; Thomas J Learch; Lianne S Gensler; John C Davis; John D Reveille; Michael H Weisman Journal: Arthritis Care Res (Hoboken) Date: 2013-02 Impact factor: 4.794