Literature DB >> 10450992

Tetrapeptide derived inhibitors of complexation of a class II MHC: fully unnatural ligands.

A B Jones1, J J Acton, A D Adams, W Yuen, E A Nichols, C D Schwartz, L S Wicker, J D Hermes.   

Abstract

Tetrapeptide derived major histocompatability (MHC) II ligands have been developed that contain no unadulterated peptide bonds. These are the 'least peptidic' ligands for any MHC protein yet reported.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10450992

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease.

Authors:  Jiang Xia; Elin Bergseng; Burkhard Fleckenstein; Matthew Siegel; Chu-Young Kim; Chaitan Khosla; Ludvig M Sollid
Journal:  Bioorg Med Chem       Date:  2007-07-25       Impact factor: 3.641

2.  Inhibition of HLA-DQ2-mediated antigen presentation by analogues of a high affinity 33-residue peptide from alpha2-gliadin.

Authors:  Jiang Xia; Matthew Siegel; Elin Bergseng; Ludvig M Sollid; Chaitan Khosla
Journal:  J Am Chem Soc       Date:  2006-02-15       Impact factor: 15.419
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.