Literature DB >> 10450970

Lobophorins A and B, new antiinflammatory macrolides produced by a tropical marine bacterium.

Z D Jiang1, P R Jensen, W Fenical.   

Abstract

Two new antiinflammatory macrolides, lobophorins A and B (1 and 2), have been isolated from fermentation broths of a marine bacterium isolated from the surface the Caribbean brown alga Lobophora variegata (Dictyotales). The new compounds, distantly related to antibiotics of the kijanimicin class, are potent inhibitors of topical PMA-induced edema in the mouse ear assay when administered either topically or IP.

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Year:  1999        PMID： 10450970     DOI： 10.1016/s0960-894x(99)00337-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  24 in total

Review 1.  Natural [4 + 2]-Cyclases.

Authors:  Byung-Sun Jeon; Shao-An Wang; Mark W Ruszczycky; Hung-Wen Liu
Journal:  Chem Rev       Date:  2016-12-01       Impact factor: 60.622

Review 2.  Targeting the unfolded protein response in head and neck and oral cavity cancers.

Authors:  Daniel W Cole; Peter F Svider; Kerolos G Shenouda; Paul B Lee; Nicholas G Yoo; Thomas M McLeod; Sean A Mutchnick; George H Yoo; Randal J Kaufman; Michael U Callaghan; Andrew M Fribley
Journal:  Exp Cell Res       Date:  2019-05-07       Impact factor: 3.905

3.  Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.

Authors:  Hua Zhang; Jess A White-Phillip; Charles E Melançon; Hyung-jin Kwon; Wei-luen Yu; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2007-11-07       Impact factor: 15.419

4.  Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts.

Authors:  Patricia G Cruz; Andrew M Fribley; Justin R Miller; Martha J Larsen; Pamela J Schultz; Renju T Jacob; Giselle Tamayo-Castillo; Randal J Kaufman; David H Sherman
Journal:  ACS Med Chem Lett       Date:  2015-07-06       Impact factor: 4.345

5.  Two Streptomyces species producing antibiotic, antitumor, and anti-inflammatory compounds are widespread among intertidal macroalgae and deep-sea coral reef invertebrates from the central Cantabrian Sea.

Authors:  Alfredo F Braña; Afredo F Braña; Hans-Peter Fiedler; Herminio Nava; Verónica González; Aida Sarmiento-Vizcaíno; Axayacatl Molina; José L Acuña; Luis A García; Gloria Blanco
Journal:  Microb Ecol       Date:  2014-10-16       Impact factor: 4.552

Review 6.  The biosynthesis of nitrogen-, sulfur-, and high-carbon chain-containing sugars.

Authors:  Chia-I Lin; Reid M McCarty; Hung-wen Liu
Journal:  Chem Soc Rev       Date:  2013-01-25       Impact factor: 54.564

7.  Pharmacological Potential of Phylogenetically Diverse Actinobacteria Isolated from Deep-Sea Coral Ecosystems of the Submarine Avilés Canyon in the Cantabrian Sea.

Authors:  Aida Sarmiento-Vizcaíno; Verónica González; Alfredo F Braña; Juan J Palacios; Luis Otero; Jonathan Fernández; Axayacatl Molina; Andreas Kulik; Fernando Vázquez; José L Acuña; Luis A García; Gloria Blanco
Journal:  Microb Ecol       Date:  2016-09-10       Impact factor: 4.552

8.  Actinoquinolines A and B, anti-inflammatory quinoline alkaloids from a marine-derived Streptomyces sp., strain CNP975.

Authors:  Hossam M Hassan; Chollaratt Boonlarppradab; William Fenical
Journal:  J Antibiot (Tokyo)       Date:  2016-05-25       Impact factor: 2.649

9.  Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp.

Authors:  Zhenjian Lin; Michael Koch; Christopher D Pond; Gaiselle Mabeza; Romell A Seronay; Gisela P Concepcion; Louis R Barrows; Baldomero M Olivera; Eric W Schmidt
Journal:  J Antibiot (Tokyo)       Date:  2013-11-13       Impact factor: 2.649

10.  Lobophorin C and D, new kijanimicin derivatives from a marine sponge-associated actinomycetal strain AZS17.

Authors:  Rong-Bian Wei; Tao Xi; Jing Li; Ping Wang; Fu-Chao Li; Yong-Cheng Lin; Song Qin
Journal:  Mar Drugs       Date:  2011-03-17       Impact factor: 5.118
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