| Literature DB >> 10450951 |
K J Duffy1, L H Ridgers, R L DesJarlais, T A Tomaszek, M J Bossard, S K Thompson, R M Keenan, D F Veber.
Abstract
The structure-based design and synthesis of lactam-constrained azapeptide inhibitors of human cathepsin K are described. Enhanced stability to proteolytic cleavage over acyclic analogues is discussed.Entities:
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Year: 1999 PMID： 10450951 DOI： 10.1016/s0960-894x(99)00322-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823