Literature DB >> 10449901

A novel human gene, encoding a potential membrane protein conserved from yeast to man, is strongly expressed in testis and cancer cell lines.

R A Veitia1, C Ottolenghi, M C Bissery, A Fellous.   

Abstract

We have characterized a novel human gene (C14orf1) which codes for a polypeptide homologous to the yeast protein Yer044c. Both the human and yeast proteins are predicted to be highly basic and to present several potential, evolutionarily conserved, transmembrane domains. C14orf1 mRNA was found to be particularly abundant in the adult testis and in several cancer cell lines. The gene maps to chromosome band 14q24. Further investigations should be performed to understand the role of C14orf1 in the testis and the significance of its strong expression in the cell lines studied here.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10449901     DOI： 10.1159/000015296

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  6 in total

1.  RNA interference characterization of proteins discovered by proteomic analysis of pancreatic cancer reveals function in cell growth and survival.

Authors:  Candy N Lee; Jenny L Heidbrink; Katherine McKinnon; Victoria Bushman; Henrik Olsen; William FitzHugh; Aiqun Li; Karen Van Orden; Tao He; Steven M Ruben; Paul A Moore
Journal:  Pancreas       Date:  2012-01       Impact factor: 3.327

Review 2.  Heat shock protein 10 and signal transduction: a "capsula eburnea" of carcinogenesis?

Authors:  Anna M Czarnecka; Claudia Campanella; Giovanni Zummo; Francesco Cappello
Journal:  Cell Stress Chaperones       Date:  2006       Impact factor: 3.667

3.  Accelerated molecular evolution of insect orthologues of ERG28/C14orf1: a link with ecdysteroid metabolism?

Authors:  R A Veitia; L D Hurst
Journal:  J Genet       Date:  2001-04       Impact factor: 1.166

4.  Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae.

Authors:  Christine M Federovitch; Ying Z Jones; Amy H Tong; Charles Boone; William A Prinz; Randolph Y Hampton
Journal:  Mol Biol Cell       Date:  2008-07-30       Impact factor: 4.138

5.  Cyclin-dependent kinase-mediated phosphorylation of breast cancer metastasis suppressor 1 (BRMS1) affects cell migration.

Authors:  Siti Nur Ain Roesley; Randy Suryadinata; Emma Morrish; Anthonius Ricardo Tan; Samah M A Issa; Jonathan S Oakhill; Ora Bernard; Danny R Welch; Boris Šarčević
Journal:  Cell Cycle       Date:  2016       Impact factor: 4.534

6.  Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

Authors:  C Mo; M Valachovic; S K Randall; J T Nickels; M Bard
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-15       Impact factor: 11.205
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.