Literature DB >> 10449607

Epstein-Barr virus genomes are found predominantly in IgA-positive B cells in the blood of healthy carriers.

B Ehlin-Henriksson1, J Z Zou, G Klein, I Ernberg.   

Abstract

B lymphocytes have been identified as the main reservoir of latent Epstein-Barr virus (EBV) in healthy virus carriers. We have established a semi-quantitative PCR method to estimate the EBV genome load in the blood B-cell subpopulation in healthy individuals. EBV DNA was detected in subfractionated IgM-, IgG- and IgA-positive B cells. Between 80% and 90% of the viral DNA was found in the IgA-positive compared with the IgA-negative fraction. Copyright 1999 Wiley-Liss, Inc.

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Year:  1999        PMID： 10449607     DOI： 10.1002/(sici)1097-0215(19990924)83:1<50::aid-ijc10>3.0.co;2-1

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  7 in total

1.  B-lymphocyte subpopulations are equally susceptible to Epstein-Barr virus infection, irrespective of immunoglobulin isotype expression.

Authors:  Barbro Ehlin-Henriksson; John Gordon; George Klein
Journal:  Immunology       Date:  2003-04       Impact factor: 7.397

Review 2.  EBV Persistence--Introducing the Virus.

Authors:  David A Thorley-Lawson
Journal:  Curr Top Microbiol Immunol       Date:  2015       Impact factor: 4.291

3.  Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection.

Authors:  Barbro Ehlin-Henriksson; Wu Liang; Alberto Cagigi; Frida Mowafi; George Klein; Anna Nilsson
Journal:  Immunology       Date:  2009-08       Impact factor: 7.397

4.  Distinct ex vivo susceptibility of B-cell subsets to epstein-barr virus infection according to differentiation status and tissue origin.

Authors:  Marcus Dorner; Franziska Zucol; Christoph Berger; Rahel Byland; Gregory T Melroe; Michele Bernasconi; Roberto F Speck; David Nadal
Journal:  J Virol       Date:  2008-03-05       Impact factor: 5.103

5.  The Effect of Antiretroviral Combination Treatment on Epstein-Barr Virus (EBV) Genome Load in HIV-Infected Patients.

Authors:  Anna M C Friis; Katarina Gyllensten; Anna Aleman; Ingemar Ernberg; Börje Åkerlund
Journal:  Viruses       Date:  2010-03-29       Impact factor: 5.818

6.  Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning.

Authors:  Qin Li; Lalit Rane; Thomas Poiret; Jiezhi Zou; Isabelle Magalhaes; Raija Ahmed; Ziming Du; Nalini Vudattu; Qingda Meng; Åsa Gustafsson-Jernberg; Jacek Winiarski; Olle Ringdén; Markus Maeurer; Mats Remberger; Ingemar Ernberg
Journal:  Oncotarget       Date:  2016-05-24

7.  Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy.

Authors:  Katerina Zachova; Petr Kosztyu; Josef Zadrazil; Karel Matousovic; Karel Vondrak; Petr Hubacek; Bruce A Julian; Zina Moldoveanu; Zdenek Novak; Klara Kostovcikova; Milan Raska; Jiri Mestecky
Journal:  Front Immunol       Date:  2020-02-28       Impact factor: 7.561
  7 in total

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