| Literature DB >> 10449511 |
R A Howe1, M Wootton, P M Bennett, A P MacGowan, T R Walsh.
Abstract
Vancomycin-sensitive, -intermediate, and -heterointermediate methicillin-resistant Staphylococcus aureus isolates were tested by using E-tests to explore the interaction of methicillin and vancomycin. For the vancomycin-intermediate and -heterointermediate strains both drugs showed antagonism at concentrations below their MICs but synergy at methicillin concentrations near the MIC. This property could be used to screen for heterointermediate S. aureus strains.Entities:
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Year: 1999 PMID: 10449511 PMCID: PMC85462
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948