Literature DB >> 10449366

Interfacial binding of secreted phospholipases A(2): more than electrostatics and a major role for tryptophan.

M H Gelb1, W Cho, D C Wilton.   

Abstract

Secreted phospholipases A(2) have similar catalytic sites, but vastly different interfacial binding surfaces that modulate their binding affinity for different kinds of phospholipid vesicles by several orders of magnitude. The structure/function principles that dictate both the differential interfacial binding and the physiological function of these enzymes are beginning to be unraveled.

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Year:  1999        PMID： 10449366     DOI： 10.1016/S0959-440X(99)80059-1

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  20 in total

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Journal:  J Am Chem Soc       Date:  2011-10-13       Impact factor: 15.419

2.  Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.

Authors:  Andrew Manford; Tian Xia; Ajay Kumar Saxena; Christopher Stefan; Fenghua Hu; Scott D Emr; Yuxin Mao
Journal:  EMBO J       Date:  2010-04-13       Impact factor: 11.598

3.  Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner.

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Journal:  J Biol Chem       Date:  2008-07-17       Impact factor: 5.157

4.  A critical beta6-beta7 loop in the pleckstrin homology domain of ceramide kinase.

Authors:  Philipp Rovina; Markus Jaritz; Siegfried Höfinger; Christine Graf; Piroska Dévay; Andreas Billich; Thomas Baumruker; Frédéric Bornancin
Journal:  Biochem J       Date:  2006-12-01       Impact factor: 3.857

5.  Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody.

Authors:  Edurne Rujas; José M M Caaveiro; Sara Insausti; Miguel García-Porras; Kouhei Tsumoto; José L Nieva
Journal:  J Biol Chem       Date:  2017-02-17       Impact factor: 5.157

6.  Changes in a phospholipid bilayer induced by the hydrolysis of a phospholipase A2 enzyme: a molecular dynamics simulation study.

Authors:  M T Hyvönen; K Oörni; P T Kovanen; M Ala-Korpela
Journal:  Biophys J       Date:  2001-02       Impact factor: 4.033

7.  Toward understanding interfacial activation of secretory phospholipase A2 (PLA2): membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA2 activation.

Authors:  S A Tatulian
Journal:  Biophys J       Date:  2001-02       Impact factor: 4.033

8.  Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway.

Authors:  H C Wong; J Mao; J T Nguyen; S Srinivas; W Zhang; B Liu; L Li; D Wu; J Zheng
Journal:  Nat Struct Biol       Date:  2000-12

9.  Molecular basis of phospholipase A2 activity toward phospholipids with sn-1 substitutions.

Authors:  Lars Linderoth; Thomas L Andresen; Kent Jørgensen; Robert Madsen; Günther H Peters
Journal:  Biophys J       Date:  2007-09-07       Impact factor: 4.033

10.  Molecular Basis of the Membrane Interaction of the β2e Subunit of Voltage-Gated Ca(2+) Channels.

Authors:  Dong-Il Kim; Mooseok Kang; Sangyeol Kim; Juhwan Lee; Yongsoo Park; Iksoo Chang; Byung-Chang Suh
Journal:  Biophys J       Date:  2015-09-01       Impact factor: 4.033
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