Literature DB >> 10448344

Management of women with recurrent genital herpes in pregnancy in Australia.

C Marks1, K Fethers, A Mindel.   

Abstract

OBJECTIVE: To document clinical practice for the management of recurrent genital herpes in pregnant women in Australia. DESIGN AND PARTICIPANTS: A questionnaire to all doctors associated with the Royal Australian College of Obstetricians and Gynaecologists. MAIN OUTCOME MEASURES: Policies for antenatal herpes screening, circumstances in which delivery by caesarean section was considered appropriate, and the use of aciclovir during pregnancy. The results were analysed by college status, sex, and whether the doctor worked in a public or private facility.
RESULTS: 2855 (67.3%) obstetricians returned questionnaires. 696 (34.3%) stated that their hospital had a policy for managing recurrent genital herpes in pregnancy: 44.5% examined the genitalia and 33.8% took cultures during pregnancy. Fellows were more likely to examine the genitalia (87% v 37%, p < 0.001), and more likely to perform antenatal viral cultures than members (75% v 30%, p < 0.001). Doctors working at private hospitals were significantly more likely to take viral cultures than doctors in public hospitals (39% v 33% p < 0.05). Doctors were asked to consider five scenarios and judge whether caesarean section would be appropriate. 96% considered that a caesarean section was appropriate in women with active herpes at the onset of labour. In the case of a recurrence of genital HSV at the time of presentation with ruptured membranes longer than 4 hours, diplomats (79%) were significantly more likely to recommend a caesarean section than fellows (64%), members (63%), or trainees (49%) (all p < or = 0.001). Where there were positive viral cultures before the onset of labour fellows (45%) were more likely than members (29%) (p = 0.005), males (62%) were more likely than females (55%) (p = 0.03), and doctors working in private hospitals (69%) were more likely than those in the public sector (54%) (p < 0.001) to recommend caesarean section.
CONCLUSION: There is considerable divergence of opinion regarding the appropriate management of recurrent genital herpes in pregnancy. The implementation of management guidelines would provide consistency of care.

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Year:  1999        PMID: 10448344      PMCID: PMC1758183          DOI: 10.1136/sti.75.1.55

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  9 in total

1.  Strategies for the prevention of neonatal infection with herpes simplex virus: a decision analysis.

Authors:  M D Libman; A Dascal; M S Kramer; J Mendelson
Journal:  Rev Infect Dis       Date:  1991 Nov-Dec

2.  Low risk of herpes simplex virus infections in neonates exposed to the virus at the time of vaginal delivery to mothers with recurrent genital herpes simplex virus infections.

Authors:  C G Prober; W M Sullender; L L Yasukawa; D S Au; A S Yeager; A M Arvin
Journal:  N Engl J Med       Date:  1987-01-29       Impact factor: 91.245

3.  A randomised placebo controlled trial of suppressive acyclovir in late pregnancy in women with recurrent genital herpes infection.

Authors:  P Brocklehurst; G Kinghorn; O Carney; K Helsen; E Ross; E Ellis; R Shen; F Cowan; A Mindel
Journal:  Br J Obstet Gynaecol       Date:  1998-03

4.  The acquisition of herpes simplex virus during pregnancy.

Authors:  Z A Brown; S Selke; J Zeh; J Kopelman; A Maslow; R L Ashley; D H Watts; S Berry; M Herd; L Corey
Journal:  N Engl J Med       Date:  1997-08-21       Impact factor: 91.245

5.  The management of recurrent genital herpes infection in pregnancy: a postal survey of obstetric practice.

Authors:  P Brocklehurst; O Carney; E Ross; A Mindel
Journal:  Br J Obstet Gynaecol       Date:  1995-10

6.  The natural history of herpes simplex virus infection of mother and newborn.

Authors:  R J Whitley; A J Nahmias; A M Visintine; C L Fleming; C A Alford
Journal:  Pediatrics       Date:  1980-10       Impact factor: 7.124

7.  A controlled trial comparing vidarabine with acyclovir in neonatal herpes simplex virus infection. Infectious Diseases Collaborative Antiviral Study Group.

Authors:  R Whitley; A Arvin; C Prober; S Burchett; L Corey; D Powell; S Plotkin; S Starr; C Alford; J Connor
Journal:  N Engl J Med       Date:  1991-02-14       Impact factor: 91.245

8.  Genital herpes during pregnancy: no lesions, no cesarean.

Authors:  S W Roberts; S M Cox; J Dax; G D Wendel; K J Leveno
Journal:  Obstet Gynecol       Date:  1995-02       Impact factor: 7.661

9.  Neonatal herpes simplex: Royal Women's Hospital 10-year experience with management guidelines for herpes in pregnancy.

Authors:  S M Garland
Journal:  Aust N Z J Obstet Gynaecol       Date:  1992-11       Impact factor: 2.100

  9 in total

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