| Literature DB >> 10448138 |
F D Finkelman1, T A Wynn, D D Donaldson, J F Urban.
Abstract
Helminth infections induce the production of type 2 cytokines, which contribute both to expulsion of the worms and inflammatory responses that can either protect or damage the host. Although IL-4 has been considered the most critical cytokine for both inflammation and protective immunity, recent observations indicate that IL-13 - a related cytokine - can have equal or even greater importance than IL-4 in inflammatory responses and host protection against infection.Entities:
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Year: 1999 PMID： 10448138 DOI： 10.1016/S0952-7915(99)80070-3
Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486