Literature DB >> 10446277

Spatial and temporal expression of p57(KIP2) during murine lens development.

F J Lovicu1, J W McAvoy.   

Abstract

The expression patterns of p57(KIP2), an important cyclin-dependent kinase inhibitor in the lens, is investigated. This study shows that the expression of p57 mRNA throughout lens morphogenesis and growth correlates with lens cell withdrawal from the cell cycle (shown by changing patterns of BrdU incorporation) and the onset of lens fibre differentiation (shown by beta-crystallin expression). p57 expression at the early stages of fibre differentiation make it a useful marker for the initiation of this process.

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Year:  1999        PMID： 10446277     DOI： 10.1016/s0925-4773(99)00106-9

Source DB:  PubMed          Journal:  Mech Dev        ISSN： 0925-4773            Impact factor:   1.882


  18 in total

Review 1.  Cell cycle regulation in the developing lens.

Authors:  Anne E Griep
Journal:  Semin Cell Dev Biol       Date:  2006-11-01       Impact factor: 7.727

Review 2.  Understanding the role of growth factors in embryonic development: insights from the lens.

Authors:  F J Lovicu; J W McAvoy; R U de Iongh
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-04-27       Impact factor: 6.237

3.  The fate of dividing cells during lens morphogenesis, differentiation and growth.

Authors:  Georgios Kallifatidis; Jessica Boros; Eun Hye H Shin; John W McAvoy; Frank J Lovicu
Journal:  Exp Eye Res       Date:  2011-03-31       Impact factor: 3.467

4.  Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation.

Authors:  Murali R Kuracha; Daniel Burgess; Ed Siefker; Jake T Cooper; Jonathan D Licht; Michael L Robinson; Venkatesh Govindarajan
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-29       Impact factor: 4.799

5.  Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.

Authors:  Blake R Chaffee; Fu Shang; Min-Lee Chang; Tracy M Clement; Edward M Eddy; Brad D Wagner; Masaki Nakahara; Shigekazu Nagata; Michael L Robinson; Allen Taylor
Journal:  Development       Date:  2014-09       Impact factor: 6.868

6.  Cell fate and differentiation of the developing ocular lens.

Authors:  Teri M S Greiling; Masamoto Aose; John I Clark
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-10-15       Impact factor: 4.799

7.  HIF-1: an age-dependent regulator of lens cell proliferation.

Authors:  Ying-Bo Shui; Jeffrey M Arbeit; Randall S Johnson; David C Beebe
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-06-27       Impact factor: 4.799

8.  Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells.

Authors:  Eri Kubo; Dhirendra P Singh; Nigar Fatma; Toshimichi Shinohara; Peggy Zelenka; Venkat N Reddy; Leo T Chylack
Journal:  Histochem Cell Biol       Date:  2003-04-12       Impact factor: 4.304

9.  MAPK/ERK1/2 and PI3-kinase signalling pathways are required for vitreous-induced lens fibre cell differentiation.

Authors:  Qian Wang; Richard Stump; John W McAvoy; Frank J Lovicu
Journal:  Exp Eye Res       Date:  2008-10-04       Impact factor: 3.467

10.  Notch signaling is required for lateral induction of Jagged1 during FGF-induced lens fiber differentiation.

Authors:  Senthil S Saravanamuthu; Chun Y Gao; Peggy S Zelenka
Journal:  Dev Biol       Date:  2009-05-27       Impact factor: 3.582
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