BACKGROUND: This longitudinal study examines the effects of alcohol use during pregnancy on the growth and gestational age at birth of 413 offspring of adolescents. METHODS: Data were collected during 1990 to 1994. The adolescents were from a prenatal clinic in Pittsburgh, PA. They were interviewed at mid-pregnancy and at delivery to obtain information on alcohol and other substance use before and during pregnancy. Infants were examined 24 to 36 hr after birth. RESULTS: The average maternal age was 16.3 (12-18) years; 68% were African American. Prenatal exposure to alcohol during the second trimester was significantly related to decreases in head circumference, birthweight, and chest circumference. There was also a significant relationship between alcohol exposure in each trimester and lower Apgar scores. All of the analyses controlled for other prenatal substance use and covariates of drinking during pregnancy. CONCLUSION: Prenatal alcohol exposure is associated with decreases in fetal growth and in APGAR scores in the offspring of adolescents.
BACKGROUND: This longitudinal study examines the effects of alcohol use during pregnancy on the growth and gestational age at birth of 413 offspring of adolescents. METHODS: Data were collected during 1990 to 1994. The adolescents were from a prenatal clinic in Pittsburgh, PA. They were interviewed at mid-pregnancy and at delivery to obtain information on alcohol and other substance use before and during pregnancy. Infants were examined 24 to 36 hr after birth. RESULTS: The average maternal age was 16.3 (12-18) years; 68% were African American. Prenatal exposure to alcohol during the second trimester was significantly related to decreases in head circumference, birthweight, and chest circumference. There was also a significant relationship between alcohol exposure in each trimester and lower Apgar scores. All of the analyses controlled for other prenatal substance use and covariates of drinking during pregnancy. CONCLUSION: Prenatal alcohol exposure is associated with decreases in fetal growth and in APGAR scores in the offspring of adolescents.
Authors: David Vaudry; Cécile Rousselle; Magali Basille; Anthony Falluel-Morel; Tommy F Pamantung; Marc Fontaine; Alain Fournier; Hubert Vaudry; Bruno J Gonzalez Journal: Proc Natl Acad Sci U S A Date: 2002-04-23 Impact factor: 11.205
Authors: F Gundogan; G Elwood; L Longato; M Tong; A Feijoo; R I Carlson; J R Wands; S M de la Monte Journal: Placenta Date: 2007-12-03 Impact factor: 3.481
Authors: Mary L Schneider; Colleen F Moore; Julie A Larson; Christina S Barr; Onofre T Dejesus; Andrew D Roberts Journal: Front Integr Neurosci Date: 2009-11-10