Literature DB >> 10443893

Phosphorus and proton magnetic resonance spectroscopy in episodic ataxia type 2.

D Sappey-Marinier1, A Vighetto, R Peyron, E Broussolle, A Bonmartin.   

Abstract

Localized phosphorus (31P) and proton (1H) magnetic resonance spectroscopy was performed in the cerebellum and the occipital lobe of 6 patients with episodic ataxia type 2. From use of 31P magnetic resonance spectroscopy, untreated patients showed decreased high-energy phosphate ratios in the cerebrum, and increased pH in the cerebellum and cerebrum, which normalized under acetazolamide. 1H magnetic resonance spectra demonstrated high lactate peaks in 3 of the 6 patients. These metabolic alterations, probably induced by the calcium channelopathy, may characterize episodic ataxia type 2.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10443893     DOI： 10.1002/1531-8249(199908)46:2<256::aid-ana17>3.0.co;2-6

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  8 in total

Review 1.  Magnetic resonance imaging biomarkers in patients with progressive ataxia: current status and future direction.

Authors:  Stuart Currie; Marios Hadjivassiliou; Ian J Craven; Iain D Wilkinson; Paul D Griffiths; Nigel Hoggard
Journal:  Cerebellum       Date:  2013-04       Impact factor: 3.847

2.  Morphometry and 1H-MR spectroscopy of the brain stem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome.

Authors:  A Ginestroni; L Guerrini; R Della Nave; C Tessa; E Cellini; M T Dotti; P Brunori; N De Stefano; S Piacentini; M Mascalchi
Journal:  AJNR Am J Neuroradiol       Date:  2007-03       Impact factor: 3.825

Review 3.  The cerebellum and migraine.

Authors:  Maurice Vincent; Nouchine Hadjikhani
Journal:  Headache       Date:  2007-06       Impact factor: 5.887

Review 4.  Episodic ataxia type 2.

Authors:  Michael Strupp; Andreas Zwergal; Thomas Brandt
Journal:  Neurotherapeutics       Date:  2007-04       Impact factor: 7.620

5.  Migraine associated vertigo.

Authors:  Yoon-Hee Cha; Robert W Baloh
Journal:  J Clin Neurol       Date:  2007-09-20       Impact factor: 3.077

Review 6.  New insights into the pathogenesis and therapeutics of episodic ataxia type 1.

Authors:  Maria Cristina D'Adamo; Sonia Hasan; Luca Guglielmi; Ilenio Servettini; Marta Cenciarini; Luigi Catacuzzeno; Fabio Franciolini
Journal:  Front Cell Neurosci       Date:  2015-08-19       Impact factor: 5.505

Review 7.  Episodic Ataxias: Faux or Real?

Authors:  Paola Giunti; Elide Mantuano; Marina Frontali
Journal:  Int J Mol Sci       Date:  2020-09-05       Impact factor: 5.923

Review 8.  Episodic ataxia type 1: a neuronal potassium channelopathy.

Authors:  Sanjeev Rajakulendran; Stephanie Schorge; Dimitri M Kullmann; Michael G Hanna
Journal:  Neurotherapeutics       Date:  2007-04       Impact factor: 7.620
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.