HYPOTHESIS: Intraoperative ultrasonography is more sensitive than preoperative and other intraoperative techniques for localizing insulinoma. DESIGN: Retrospective review. SETTING: A tertiary referral center. PATIENTS: All patients with a biochemical diagnosis of organic hyperinsulinism who were referred to University of California, San Francisco, from 1975 to 1998. METHODS: Sensitivities of the localization techniques for insulinoma were evaluated. RESULTS: The sensitivities of tumor localization with arteriography, computed tomography, preoperative ultrasonography, magnetic resonance imaging, magnetic resonance imaging with gadolinium, transhepatic venous sampling, palpation, and intraoperative ultrasonography were 47%, 24%, 50%, 30%, 40%, 55%, 76%, and 91%, respectively. Nine of the 11 nonpalpable and nonvisible tumors at operation were localized by intraoperative ultrasonography. CONCLUSION: The currently available preoperative localization tests are not reliable enough to be recommended when intraoperative ultrasonography is available.
HYPOTHESIS: Intraoperative ultrasonography is more sensitive than preoperative and other intraoperative techniques for localizing insulinoma. DESIGN: Retrospective review. SETTING: A tertiary referral center. PATIENTS: All patients with a biochemical diagnosis of organic hyperinsulinism who were referred to University of California, San Francisco, from 1975 to 1998. METHODS: Sensitivities of the localization techniques for insulinoma were evaluated. RESULTS: The sensitivities of tumor localization with arteriography, computed tomography, preoperative ultrasonography, magnetic resonance imaging, magnetic resonance imaging with gadolinium, transhepatic venous sampling, palpation, and intraoperative ultrasonography were 47%, 24%, 50%, 30%, 40%, 55%, 76%, and 91%, respectively. Nine of the 11 nonpalpable and nonvisible tumors at operation were localized by intraoperative ultrasonography. CONCLUSION: The currently available preoperative localization tests are not reliable enough to be recommended when intraoperative ultrasonography is available.
Authors: Daniel Casanova; Manuel G Polavieja; Angel Naranjo; Fernando Pardo; Fernando Rotellar; Francisco Gonzalez; Cristina Luzuriaga; Sara Regaño; Julio Freijanes Journal: Langenbecks Arch Surg Date: 2007-03-21 Impact factor: 3.445
Authors: Brian K P Goh; London L P J Ooi; Peng-Chung Cheow; Yu-Meng Tan; Hock-Soo Ong; Yaw-Fui A Chung; Pierce K H Chow; Wai-Keong Wong; Khee-Chee Soo Journal: J Gastrointest Surg Date: 2009-03-17 Impact factor: 3.452
Authors: Mehrdad Nikfarjam; Andrew L Warshaw; Lloyd Axelrod; Vikram Deshpande; Sarah P Thayer; Cristina R Ferrone; Carlos Fernández-del Castillo Journal: Ann Surg Date: 2008-01 Impact factor: 12.969