OBJECTIVE: Poor scholastic performance is known to pre-date adult schizophrenia. We studied the 1966 North Finland general population birth cohort (n = 11017) in order to determine whether excellent school performance was a risk or protective factor. METHOD: Data on school marks at the age of 16 years were linked to data on psychiatric morbidity. In total, 89 subjects (58 boys) developed DSM-III-R schizophrenia between the ages of 16 and 28 years. RESULTS: Six (11%) of the pre-schizophrenic boys (6/54) had excellent mean school marks, compared to only 3% (166/5245) of the comparison group (OR 3.8; 95% CI 1.6-9.3, adjusted for parental social class, place of residence and birth order). CONCLUSION: These results may be a chance phenomenon and require replication. However, adult schizophrenia may be linked to excellent school performance. This result may be relevant both to the preservation of schizophrenia in the population, and to mechanisms of developing schizophrenia.
OBJECTIVE: Poor scholastic performance is known to pre-date adult schizophrenia. We studied the 1966 North Finland general population birth cohort (n = 11017) in order to determine whether excellent school performance was a risk or protective factor. METHOD: Data on school marks at the age of 16 years were linked to data on psychiatric morbidity. In total, 89 subjects (58 boys) developed DSM-III-R schizophrenia between the ages of 16 and 28 years. RESULTS: Six (11%) of the pre-schizophrenicboys (6/54) had excellent mean school marks, compared to only 3% (166/5245) of the comparison group (OR 3.8; 95% CI 1.6-9.3, adjusted for parental social class, place of residence and birth order). CONCLUSION: These results may be a chance phenomenon and require replication. However, adult schizophrenia may be linked to excellent school performance. This result may be relevant both to the preservation of schizophrenia in the population, and to mechanisms of developing schizophrenia.
Authors: Warrick J Brewer; Stephen J Wood; Lisa J Phillips; Shona M Francey; Christos Pantelis; Alison R Yung; Barbara Cornblatt; Patrick D McGorry Journal: Schizophr Bull Date: 2006-06-16 Impact factor: 9.306
Authors: Ashleigh Lin; Patsy Di Prinzio; Deidra Young; Peter Jacoby; Andrew Whitehouse; Flavie Waters; Assen Jablensky; Vera A Morgan Journal: Schizophr Bull Date: 2016-04-30 Impact factor: 9.306
Authors: Matti Isohanni; Irene Isohanni; Hannu Koponen; Johanna Koskinen; Pekka Laine; Erika Lauronen; Jouko Miettunen; Pirjo Mäki; Kaisa Riala; Sami Räsänen; Kaisa Saari; Pekka Tienari; Juha Veijola; Graham Murray Journal: Curr Psychiatry Rep Date: 2004-06 Impact factor: 5.285