Literature DB >> 10441791

Effects of ethanol extract of Moringa stenopetala leaves on guinea-pig and mouse smooth muscle.

Y Mekonnen1.   

Abstract

The fresh leaf ethanol (LE) extract of Moringa stenopetala was tested in guinea-pig ileum and mouse duodenum and in uterus strips. There were significant dose and time dependent reductions of the acetylcholine (AC) response with initial stimulatory effects in both the guinea-pig ileum and the mouse duodenum preparations. Spontaneous rhythmic contractions were greatly reduced, suggesting an antispasmodic property of the crude LE extract. The LE extract showed some oxytocic activity on uterus strips of guinea-pigs and mice. The results are indicative of the traditional use of the leaves of Moringa stenopetala for stomach pain and to expel retained placentae by women. Copyright 1999 John Wiley & Sons, Ltd.

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Year:  1999        PMID： 10441791     DOI： 10.1002/(sici)1099-1573(199908/09)13:5<442::aid-ptr476>3.0.co;2-7

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  9 in total

1.  Antifertility effect of aqueous and ethanol extracts of the leaves and roots of Asparagus africanus in rats.

Authors:  Geremew Tafesse; Yalemtsehay Mekonnen; Eyasu Makonnen
Journal:  Afr Health Sci       Date:  2006-06       Impact factor: 0.927

2.  In vivo and in vitro hypotensive effect of aqueous extract of Moringa stenopetala.

Authors:  M Mengistu; Y Abebe; Y Mekonnen; T Tolessa
Journal:  Afr Health Sci       Date:  2012-12       Impact factor: 0.927

3.  Antidiabetic activities of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin-induced diabetic rats.

Authors:  Alemayehu Toma; Eyasu Makonnen; Yelamtsehay Mekonnen; Asfaw Debella; Sirichai Adisakwattana
Journal:  BMC Complement Altern Med       Date:  2015-07-18       Impact factor: 3.659

4.  Antifertility activity of Thevetia peruviana (Pers.) K. Schum leaf in female Sprague-Dawley rat.

Authors:  Jhuma Samanta; Snehendu Bhattacharya; Avtar C Rana
Journal:  Indian J Pharmacol       Date:  2016 Nov-Dec       Impact factor: 1.200

5.  Diuretic activity of the aqueous crude extract and hot tea infusion of Moringa stenopetala (Baker f.) Cufod. leaves in rats.

Authors:  Netsanet Fekadu; Hirut Basha; Asfaw Meresa; Sileshi Degu; Biruktawit Girma; Bekesho Geleta
Journal:  J Exp Pharmacol       Date:  2017-06-21

6.  In vitro vasodilatory activity and possible mechanisms of the crude extracts and fractions of Moringa stenopetala (Baker f.) Cufod. leaves in isolated thoracic aorta of guinea pigs.

Authors:  Bekesho Geleta; Eyasu Makonnen; Asfaw Debella; Abiy Abebe; Netsanet Fekadu
Journal:  J Exp Pharmacol       Date:  2016-10-12

7.  Evaluation of Antihyperglycemic Effect of Extract of Moringa stenopetala (Baker f.) Aqueous Leaves on Alloxan-Induced Diabetic Rats.

Authors:  Samuel Woldekidan; Abay Mulu; Wondwossen Ergetie; Frehiwot Teka; Asfaw Meressa; Ashenif Tadele; Abiy Abebe; Worku Gemechu; Negero Gemeda; Rekik Ashebir; Meron Sileshi; Yoseph Tolcha
Journal:  Diabetes Metab Syndr Obes       Date:  2021-01-15       Impact factor: 3.168

8.  Intestinal α-glucosidase and some pancreatic enzymes inhibitory effect of hydroalcholic extract of Moringa stenopetala leaves.

Authors:  Alemayehu Toma; Eyasu Makonnen; Yelamtsehay Mekonnen; Asfaw Debella; Sirichai Addisakwattana
Journal:  BMC Complement Altern Med       Date:  2014-06-03       Impact factor: 3.659

9.  Toxicity of Methanolic Extracts of Seeds of Moringa stenopetala, Moringaceae in Rat Embryos and Fetuses.

Authors:  Daniel Teshome; Chalachew Tiruneh; Gete Berihun
Journal:  Biomed Res Int       Date:  2021-02-09       Impact factor: 3.411
  9 in total

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