| Literature DB >> 10441774 |
J Y Lim1, K Ishiguro, I Kubo.
Abstract
By bioassay-guided fractionation using mushroom tyrosinase, p-coumaric acid was characterized as the principal tyrosinase inhibitor from the fresh leaves of Panax ginseng (Araliaceae). It inhibited the oxidation of L-tyrosine more strongly than that of L-3, 4-dihydroxyphenylalanine (L-DOPA) by this enzyme. On the basis of this finding, various related phenylpropanoid analogues were also tested in order to gain new insights into their structural criteria. Copyright 1999 John Wiley & Sons, Ltd.Entities:
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Year: 1999 PMID: 10441774 DOI: 10.1002/(sici)1099-1573(199908/09)13:5<371::aid-ptr453>3.0.co;2-l
Source DB: PubMed Journal: Phytother Res ISSN: 0951-418X Impact factor: 5.878