Literature DB >> 10441278

Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs.

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Abstract

Cytotoxic agent processing assumes certain prerequisites in order to guarantee a high level of security for both personnel and the material used. A lab-scale unit designed for the production and analysis of nanosuspensions of cytotoxic agents has been in use for more than three years. This design encompasses equipment, exhaust systems, materials used and measures for staff security, and this lab suite may also be used in applications that involve production in aseptic conditions.

Entities:  

Year:  1999        PMID： 10441278     DOI： 10.1016/s1461-5347(99)00177-7

Source DB:  PubMed          Journal:  Pharm Sci Technolo Today        ISSN： 1461-5347


  11 in total

Review 1.  Improved delivery of poorly soluble compounds using nanoparticle technology: a review.

Authors:  Sandeep Kalepu; Vijaykumar Nekkanti
Journal:  Drug Deliv Transl Res       Date:  2016-06       Impact factor: 4.617

2.  Understanding the structure and stability of paclitaxel nanocrystals.

Authors:  Jiexin Deng; Leaf Huang; Feng Liu
Journal:  Int J Pharm       Date:  2010-02-16       Impact factor: 5.875

3.  Comparison of Paliperidone Palmitate from Different Crystallization Processes and Effect on Formulations In Vitro and In Vivo.

Authors:  Junfeng Shi; Dan Wang; Yang Tian; Zengming Wang; Jing Gao; Nan Liu; Xiang Gao; Aiping Zheng; Hui Zhang; Meixian Xiang
Journal:  Pharmaceutics       Date:  2022-05-20       Impact factor: 6.525

Review 4.  Application of drug nanocrystal technologies on oral drug delivery of poorly soluble drugs.

Authors:  Lei Gao; Guiyang Liu; Jianli Ma; Xiaoqing Wang; Liang Zhou; Xiang Li; Fang Wang
Journal:  Pharm Res       Date:  2012-10-17       Impact factor: 4.200

5.  Preparation and in vitro/in vivo evaluation of felodipine nanosuspension.

Authors:  Bhanu P Sahu; Malay K Das
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2013-11-07       Impact factor: 2.441

6.  Cyclosporine a-nanosuspension: formulation, characterization and in vivo comparison with a marketed formulation.

Authors:  Mahendra Nakarani; Priyal Patel; Jayvadan Patel; Pankaj Patel; Rayasa S R Murthy; Subhash S Vaghani
Journal:  Sci Pharm       Date:  2010-04-26

7.  Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery.

Authors:  Yonglu Wang; Xueming Li; Liyao Wang; Yuanlong Xu; Xiaodan Cheng; Ping Wei
Journal:  Int J Nanomedicine       Date:  2011-07-13

8.  Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112.

Authors:  Dong Dong; Xiao Wang; Huailing Wang; Xingwang Zhang; Yifei Wang; Baojian Wu
Journal:  Int J Nanomedicine       Date:  2015-03-31

Review 9.  Performance Parameters and Characterizations of Nanocrystals: A Brief Review.

Authors:  Manasi M Chogale; Vinod N Ghodake; Vandana B Patravale
Journal:  Pharmaceutics       Date:  2016-08-30       Impact factor: 6.321

10.  Preparation, characterization and pharmacokinetics of cyadox nanosuspension.

Authors:  Adeel Sattar; Dongmei Chen; Lishun Jiang; Yuanhu Pan; Yanfei Tao; Lingli Huang; Zhenli Liu; Shuyu Xie; Zonghui Yuan
Journal:  Sci Rep       Date:  2017-05-23       Impact factor: 4.379
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