| Literature DB >> 10439403 |
F Abaitua1, A Rementería, R San Millan, A Eguzkiza, J A Rodriguez, J Pontón, M J Sevilla.
Abstract
The in vitro effect of nitric oxide (NO) and nitrite on blastoconidia and hyphae of Candida albicans was studied. Sodium nitroprusside (SNP) and S-nitroso-N-acetylpenicillamine (SNAP) were used as NO donors. Both minimal and complex media at two pH values, 7.0 and 4.5, were used for the assays. Blastoconidia were more susceptible than hyphae to NO. The NO effect on blastoconidia was greater at acidic pH. Nitrite affected the viability of blastoconidia in complex medium. The percentage germination and the relative rate of elongation of hyphae were both enhanced when NO was present in acidic conditions.Entities:
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Year: 1999 PMID： 10439403 DOI： 10.1099/13500872-145-7-1641
Source DB: PubMed Journal: Microbiology ISSN： 1350-0872 Impact factor: 2.777