Literature DB >> 10436867

Zileuton, a leukotriene synthesis inhibitor in the management of chronic asthma. Clinical pharmacokinetics and safety.

L M Dubé1, L J Swanson, W Awni.   

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Year:  1999        PMID: 10436867     DOI: 10.1007/BF02737605

Source DB:  PubMed          Journal:  Clin Rev Allergy Immunol        ISSN: 1080-0549            Impact factor:   8.667


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  27 in total

1.  Assessment of the pharmacokinetic interaction between zileuton and digoxin in humans.

Authors:  W M Awni; Z Hussein; J H Cavanaugh; G R Granneman; L M Dubé
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

2.  The pharmacokinetics of zileuton in healthy young and elderly volunteers.

Authors:  R A Braeckman; G R Granneman; C S Locke; J M Machinist; J H Cavannaugh; W M Awni
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

3.  The effect of food on the pharmacokinetics of zileuton.

Authors:  W M Awni; J H Cavanaugh; G Witt; G R Granneman; L M Dubé
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

4.  The pharmacokinetic and pharmacodynamic interaction between zileuton and terfenadine.

Authors:  W M Awni; J H Cavanaugh; P Leese; J Kasier; G Cao; C S Locke; L M Dube
Journal:  Eur J Clin Pharmacol       Date:  1997       Impact factor: 2.953

5.  Effect of zileuton on theophylline pharmacokinetics.

Authors:  G R Granneman; R A Braeckman; C S Locke; J H Cavanaugh; L M Dubé; W M Awni
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

6.  Evaluation of the diurnal variation in the pharmacokinetics of zileuton in healthy volunteers.

Authors:  W M Awni; C Locke; L M Dube; J H Cavanaugh
Journal:  J Clin Pharmacol       Date:  1997-05       Impact factor: 3.126

7.  Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.

Authors:  K Yoshimoto; H Echizen; K Chiba; M Tani; T Ishizaki
Journal:  Br J Clin Pharmacol       Date:  1995-04       Impact factor: 4.335

Review 8.  Hepatic toxicity of nonsteroidal anti-inflammatory drugs.

Authors:  J H Lewis
Journal:  Clin Pharm       Date:  1984 Mar-Apr

9.  The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma.

Authors:  E Israel; P Rubin; J P Kemp; J Grossman; W Pierson; S C Siegel; D Tinkelman; J J Murray; W Busse; A T Segal; J Fish; H B Kaiser; D Ledford; S Wenzel; R Rosenthal; J Cohn; C Lanni; H Pearlman; P Karahalios; J M Drazen
Journal:  Ann Intern Med       Date:  1993-12-01       Impact factor: 25.391

10.  Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation.

Authors:  B Samuelsson
Journal:  Science       Date:  1983-05-06       Impact factor: 47.728

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  8 in total

Review 1.  Leukotrienes and airway inflammation.

Authors:  Katsuhide Okunishi; Marc Peters-Golden
Journal:  Biochim Biophys Acta       Date:  2011-02-23

Review 2.  Proinflammatory Pathways in the Pathogenesis of Asthma.

Authors:  R Stokes Peebles; Mark A Aronica
Journal:  Clin Chest Med       Date:  2019-03       Impact factor: 2.878

3.  Investigating the selectivity of metalloenzyme inhibitors.

Authors:  Joshua A Day; Seth M Cohen
Journal:  J Med Chem       Date:  2013-10-14       Impact factor: 7.446

4.  Placenta growth factor induces 5-lipoxygenase-activating protein to increase leukotriene formation in sickle cell disease.

Authors:  Nitin Patel; Caryn S Gonsalves; Minyang Yang; Punam Malik; Vijay K Kalra
Journal:  Blood       Date:  2008-10-22       Impact factor: 22.113

5.  Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury.

Authors:  Pietro Roversi; Bernhard Ryffel; Dieudonnée Togbe; Isabelle Maillet; Mauro Teixeira; Nurfilza Ahmat; Guido C Paesen; Olga Lissina; Wilhelm Boland; Kerstin Ploss; Joseph J E Caesar; Susanne Leonhartsberger; Susan M Lea; Miles A Nunn
Journal:  J Biol Chem       Date:  2013-04-26       Impact factor: 5.157

6.  Multi-Walled Carbon Nanotubes Augment Allergic Airway Eosinophilic Inflammation by Promoting Cysteinyl Leukotriene Production.

Authors:  Sophia Carvalho; Maria Ferrini; Lou Herritt; Andrij Holian; Zeina Jaffar; Kevan Roberts
Journal:  Front Pharmacol       Date:  2018-06-05       Impact factor: 5.810

7.  New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition.

Authors:  Audrey Isabel Chiasson; Samuel Robichaud; Fanta J Ndongou Moutombi; Mathieu P A Hébert; Maroua Mbarik; Marc E Surette; Mohamed Touaibia
Journal:  Molecules       Date:  2020-10-14       Impact factor: 4.411

8.  Side Effects of Leukotriene Receptor Antagonists in Asthmatic Children.

Authors:  Semiha Bahceci Erdem; Hikmet Tekin Nacaroglu; Canan Sule Unsal Karkiner; Ilker Gunay; Demet Can
Journal:  Iran J Pediatr       Date:  2015-10-06       Impact factor: 0.364

  8 in total

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