| Literature DB >> 10435442 |
K Thangaraj1, G V Ramana, L Singh.
Abstract
Y-chromosome polymorphism using short tandem repeat (STR) markers on 94 normal males belonging to the Brahmin and Kamma caste populations of Andhra Pradesh, India, and Siddis, a migrant population from Africa, inhabiting Hyderabad, India, revealed heterogeneity as indicated by network analysis. We have observed population-specific haplotypes and alleles. Analysis of Y-Alu polymorphism (YAP) in Siddis showed the presence of Alu insertion in 40% of the individuals. However, YAP insertion was not found in Brahmins and Kammas. The dendrogram based on hypervariable region I (HVR I) of the displacement loop (D-loop) sequence of mitochondrial DNA (mtDNA) of Siddis showed genetic relationships to African populations. YAP and mtDNA analysis of Siddis also confirmed their immigration from Africa.Entities:
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Year: 1999 PMID: 10435442 DOI: 10.1002/(SICI)1522-2683(19990101)20:8<1743::AID-ELPS1743>3.0.CO;2-V
Source DB: PubMed Journal: Electrophoresis ISSN: 0173-0835 Impact factor: 3.535