Literature DB >> 10433480

The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice.

M H Pourgholami1, S Majzoob, M Javadi, M Kamalinejad, G H Fanaee, M Sayyah.   

Abstract

This study investigates anticonvulsant effects of an essential oil of the fruits of Pimpinella anisum (Umbelliferae), a folkloric remedy in the Iranian traditional medicine, against seizures induced by pentylenetetrazole (PTZ) or maximal electroshock (MES) in male mice. The essential oil suppressed tonic convulsions induced by PTZ or MES. It also elevated the threshold of PTZ-induced clonic convulsions in mice. The essential oil produced motor impairment. However, this effect was not observed at the doses and time courses needed for anticonvulsant activity.

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Year:  1999        PMID： 10433480     DOI： 10.1016/s0378-8741(98)00161-5

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  16 in total

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Review 3.  Awareness and current knowledge of epilepsy.

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Journal:  Metab Brain Dis       Date:  2019-10-11       Impact factor: 3.584

4.  Anticonvulsant and neuroprotective effects of Pimpinella anisum in rat brain.

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5.  Effect of Gentiana olivieri on experimental epilepsy models.

Authors:  Mustafa Aslan; Didem Delioman Orhan; Nilufer Orhan
Journal:  Pharmacogn Mag       Date:  2011-10       Impact factor: 1.085

6.  An in vivo and in vitro investigation on hepatoprotective effects of Pimpinella anisum seed essential oil and extracts against carbon tetrachloride-induced toxicity.

Authors:  Akram Jamshidzadeh; Reza Heidari; Mojtaba Razmjou; Forouzan Karimi; Mahmood Reza Moein; Omid Farshad; Amin Reza Akbarizadeh; Mohammad Reza Houshangi Shayesteh
Journal:  Iran J Basic Med Sci       Date:  2015-02       Impact factor: 2.699

7.  Review of Pharmacological Properties and Chemical Constituents of Pimpinella anisum.

Authors:  Asie Shojaii; Mehri Abdollahi Fard
Journal:  ISRN Pharm       Date:  2012-07-16

8.  Pimpinella anisum in the treatment of functional dyspepsia: A double-blind, randomized clinical trial.

Authors:  S Ashraffodin Ghoshegir; Mohammad Mazaheri; Alireza Ghannadi; Awat Feizi; Mahmoud Babaeian; Maryam Tanhaee; Mehrdad Karimi; Peyman Adibi
Journal:  J Res Med Sci       Date:  2015-01       Impact factor: 1.852

Review 9.  Efficacy of Iranian traditional medicine in the treatment of epilepsy.

Authors:  Mehri Abdollahi Fard; Asie Shojaii
Journal:  Biomed Res Int       Date:  2013-07-07       Impact factor: 3.411

10.  Anticonvulsant Effect of the Aqueous Extract and Essential Oil of Carum Carvi L. Seeds in a Pentylenetetrazol Model of Seizure in Mice.

Authors:  Alireza Showraki; Masoumeh Emamghoreishi; Somayeh Oftadegan
Journal:  Iran J Med Sci       Date:  2016-05
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