Literature DB >> 10431156

Naturally occurring antibodies to cholesterol: a new theory of LDL cholesterol metabolism.

C R Alving1, N M Wassef.   

Abstract

Although low-density lipoprotein (LDL) receptors regulate the disposition of two-thirds of circulating serum LDL cholesterol, non-LDL receptor mechanisms account for removal of one-third. Here, Carl Alving and Nabila Wassef propose that naturally occurring antibodies to cholesterol in normal human plasma also contribute to LDL cholesterol turnover by opsonizing LDL and other lipoproteins containing 'bad' cholesterol for removal by complement receptors.

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Year:  1999        PMID： 10431156     DOI： 10.1016/s0167-5699(99)01496-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  11 in total

1.  Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia.

Authors:  Sarinnapha Vasunilashorn; Eileen M Crimmins; Jung Ki Kim; Jeff Winking; Michael Gurven; Hillard Kaplan; Caleb E Finch
Journal:  Am J Hum Biol       Date:  2010 Nov-Dec       Impact factor: 1.937

2.  New cholesterol-specific antibodies remodel HIV-1 target cells' surface and inhibit their in vitro virus production.

Authors:  Zoltán Beck; Andrea Balogh; Andrea Kis; Emese Izsépi; László Cervenak; Glória László; Adrienn Bíró; Károly Liliom; Gábor Mocsár; György Vámosi; George Füst; Janos Matko
Journal:  J Lipid Res       Date:  2009-08-04       Impact factor: 5.922

3.  Phosphorylcholine-dependent cross-reactivity between dental plaque bacteria and oxidized low-density lipoproteins.

Authors:  H A Schenkein; C R Berry; D Purkall; J A Burmeister; C N Brooks; J G Tew
Journal:  Infect Immun       Date:  2001-11       Impact factor: 3.441

4.  Vaccines with the MF59 adjuvant do not stimulate antibody responses against squalene.

Authors:  Giuseppe Del Giudice; Elena Fragapane; Roberto Bugarini; Maninder Hora; Thomas Henriksson; Emanuela Palla; Derek O'hagan; John Donnelly; Rino Rappuoli; Audino Podda
Journal:  Clin Vaccine Immunol       Date:  2006-09

5.  Monoclonal antibodies to phosphatidylinositol phosphate neutralize human immunodeficiency virus type 1: role of phosphate-binding subsites.

Authors:  Bruce K Brown; Nicos Karasavvas; Zoltan Beck; Gary R Matyas; Deborah L Birx; Victoria R Polonis; Carl R Alving
Journal:  J Virol       Date:  2006-12-06       Impact factor: 5.103

6.  A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG.

Authors:  L L Rumfelt; D Avila; M Diaz; S Bartl; E C McKinney; M F Flajnik
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

7.  Anti-cholesterol antibody levels in hereditary angioedema.

Authors:  Lilian Varga; Adrienn Bíró; Gábor Széplaki; Luca Tóth; Anna Horváth; George Füst; Henriette Farkas
Journal:  J Cell Mol Med       Date:  2007 Nov-Dec       Impact factor: 5.310

Review 8.  Cardiovascular disease and type 2 diabetes in evolutionary perspective: a critical role for helminths?

Authors:  Michael D Gurven; Benjamin C Trumble; Jonathan Stieglitz; Aaron D Blackwell; David E Michalik; Caleb E Finch; Hillard S Kaplan
Journal:  Evol Med Public Health       Date:  2016-09-25

9.  The Effect of Helminth Infections and Their Treatment on Metabolic Outcomes: Results of a Cluster-Randomized Trial.

Authors:  Richard E Sanya; Emily L Webb; Christopher Zziwa; Robert Kizindo; Moses Sewankambo; Josephine Tumusiime; Esther Nakazibwe; Gloria Oduru; Emmanuel Niwagaba; Prossy Kabuubi Nakawungu; Joyce Kabagenyi; Jacent Nassuuna; Bridgious Walusimbi; Irene Andia-Biraro; Alison M Elliott
Journal:  Clin Infect Dis       Date:  2020-07-27       Impact factor: 9.079

10.  Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro.

Authors:  Barry W Neun; Yechezkel Barenholz; Janos Szebeni; Marina A Dobrovolskaia
Journal:  Molecules       Date:  2018-07-12       Impact factor: 4.411
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