Neural connections of the pontine reticular formation, which connects reciprocally with the nucleus prepositus hypoglossi in the rat.

The pontine reticular formation connected with the nucleus prepositus hypoglossi was studied in the rat using anterograde and retrograde tracer techniques. The area reciprocally connected with the nucleus prepositus hypoglossi was evident in the pontine reticular formation of the rat. The region had intensive reciprocal connections with the ipsilateral subthalamic region, the contralateral pontine reticular formation and the nucleus prepositus hypoglossi. Furthermore, it was confirmed that the region received cholinergic projections mainly from the pedunculopontine tegmental nucleus and the laterodorsal tegmental nucleus, and aminergic projections from the dopaminergic cell groups A13 and A11, noradrenergic cell groups A7, A6 and A5, and the serotoninergic B9 cell group. This region in the rat was considered to be the preoculomotor structure in the function of horizontal gaze corresponding to the paramedian pontine reticular formation in other animals.