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Literature DB >> 104301

Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie.

Abstract

The titers of several preparations of kuru. Creutzfeldt-Jacob disease, and scrapie viruses were reduced by only 1/10th or less by high doses of gamma radiation of 50 kGy and by only 1/10th-1/1000th or less for 200 kGy. This unusual radiation resistance of the two human viruses further links them with the scrapie virus and suggests that the genetic information of all three viruses is considerably smaller than that of any other known viruses of mammals.

Entities: Species

Mesh：

Substances：
Prions

Year: 1978 PMID： 104301 PMCID： PMC393162 DOI： 10.1073/pnas.75.12.6268

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

7 in total

1. A new and rapid method for isolating viruses by selective fluorocarbon deproteinization.

Authors: A E GESSLER; C E BENDER; M C PARKINSON
Journal: Trans N Y Acad Sci Date: 1956-06

2. Unconventional viruses and the origin and disappearance of kuru.

Authors: D C Gajdusek
Journal: Science Date: 1977-09-02 Impact factor: 47.728

3. Does the agent of scrapie replicate without nucleic acid?

Authors: T Alper; W A Cramp; D A Haig; M C Clarke
Journal: Nature Date: 1967-05-20 Impact factor: 49.962

4. The exceptionally small size of the scrapie agent.

Authors: T Alper; D A Haig; M C Clarke
Journal: Biochem Biophys Res Commun Date: 1966-02-03 Impact factor: 3.575

5. Partial purification of the scrapie agent from mouse brain by pressure disruption and zonal centrifugation in sucrose-sodium chloride gradients.

Authors: A N Siakotos; D C Gajdusek; C J Gibbs; R D Traub; C Bucana
Journal: Virology Date: 1976-03 Impact factor: 3.616

6. Inactivation of the scrapie agent by near monochromatic ultraviolet light.

Authors: R Latarjet; B Muel; D A Haig; M C Clarke; T Alper
Journal: Nature Date: 1970-09-26 Impact factor: 49.962

7. Potato spindle tuber viroid. XI. A comparison of the ultraviolet light sensitivities of PSTV, tobacco ringspot virus, and its satellite.

Authors: T O Diener; I R Schneider; D R Smith
Journal: Virology Date: 1974-02 Impact factor: 3.616

7 in total

23 in total

1. Quantifying the reduction in potential health risks by determining the sensitivity of poliovirus type 1 chat strain and rotavirus SA-11 to electron beam irradiation of iceberg lettuce and spinach.

Authors: Ana Cecilia Espinosa; Palmy Jesudhasan; René Arredondo; Martha Cepeda; Marisa Mazari-Hiriart; Kristi D Mena; Suresh D Pillai
Journal: Appl Environ Microbiol Date: 2011-12-16 Impact factor: 4.792

Review 2. Prion propagation: the role of protein dynamics.

Authors: John A Pezza; Tricia R Serio
Journal: Prion Date: 2007-01-10 Impact factor: 3.931

Review 3. Prion liposomes.

Authors: R Gabizon; S B Prusiner
Journal: Biochem J Date: 1990-02-15 Impact factor: 3.857

4. Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants.

Authors: P E Bendheim; J M Bockman; M P McKinley; D T Kingsbury; S B Prusiner
Journal: Proc Natl Acad Sci U S A Date: 1985-02 Impact factor: 11.205

5. Progressive fatal dementia (Creutzfeldt-Jakob disease) in a patient who received homograft tissue for tympanic membrane closure.

Authors: R A Tange; D Troost; M Limburg
Journal: Eur Arch Otorhinolaryngol Date: 1990 Impact factor: 2.503

6. Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues.

Authors: N K Robakis; P R Sawh; G C Wolfe; R Rubenstein; R I Carp; M A Innis
Journal: Proc Natl Acad Sci U S A Date: 1986-09 Impact factor: 11.205

7. Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035].

Authors: B Hay; R A Barry; I Lieberburg; S B Prusiner; V R Lingappa
Journal: Mol Cell Biol Date: 1987-02 Impact factor: 4.272