Literature DB >> 10428993

Has asthma medication use in children become more frequent, more appropriate, or both?

D C Goodman1, P Lozano, T A Stukel, Ch Chang, J Hecht.   

Abstract

OBJECTIVE: Despite national initiatives to improve asthma medical treatment, the appropriateness of physician prescribing for children with asthma remains unknown. This study measures trends and recent patterns in the pediatric use of medications approved for reversible obstructive airway disease (asthma medications).
DESIGN: Population-based longitudinal and cross-sectional analyses. Setting. A nonprofit staff model health maintenance organization located in the Puget Sound area of Washington state. PARTICIPANTS: Children 0 to 17 years of age enrolled continuously during any one of the years from 1984 to 1993 (N = 83 232 in 1993). PRIMARY OUTCOME MEASURES. Percent of enrollees filling prescriptions for asthma medications and fill rates by medication class and estimated duration of inhaled antiinflammatory medication use.
RESULTS: Between 1984 and 1993, the frequency of asthma medication use increased: the percent of children filling any asthma medication prescription increased from 4. 0% to 8.1%, whereas the percent filling an inhaled antiinflammatory inhaler rose from 0.4% to 2.4%. In contrast, the intensity of inhaled antiinflammatory use decreased among users; 37% of users filled more than two inhalers during the year in 1984, and 29% in 1993. In high beta-agonist users (filling more than two beta-agonist inhalers each quarter per year), the estimated duration of inhaled antiinflammatory use increased slightly from a mean of 4.1 months per year in 1984-1986 to 5.0 months in 1991-1993; estimated duration of use in adolescents 10 to 17 years of age was approximately half that of children 5 to 9 years of age.
CONCLUSIONS: The proportion of children using asthma medications increased substantially during the study period, but the use of inhaled antiinflammatory medication per patient remained low even for those using large amounts of inhaled beta-agonists. These findings suggest that most asthma medications were used by children with mild lower airway symptoms and that inhaled antiinflammatory medication use in children with more severe disease fell short of national guidelines.

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Year:  1999        PMID: 10428993     DOI: 10.1542/peds.104.2.187

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  18 in total

Review 1.  Management of chronic disease by practitioners and patients: are we teaching the wrong things?

Authors:  N M Clark; M Gong
Journal:  BMJ       Date:  2000-02-26

2.  Income-based drug benefit policy: impact on receipt of inhaled corticosteroid prescriptions by Manitoba children with asthma.

Authors:  A L Kozyrskyj; C A Mustard; M S Cheang; F E Simons
Journal:  CMAJ       Date:  2001-10-02       Impact factor: 8.262

3.  Clinical effectiveness research in managed-care systems: lessons from the Pediatric Asthma Care PORT. Patient Outcomes Research Team.

Authors:  Jonathan A Finkelstein; Paula Lozano; Kachen A Streiff; Kelly E Arduino; Cynthia A Sisk; Edward H Wagner; Kevin B Weiss; Thomas S Inui
Journal:  Health Serv Res       Date:  2002-06       Impact factor: 3.402

4.  Effects of a school-based intervention for urban adolescents with asthma. A controlled trial.

Authors:  Jean-Marie Bruzzese; Beverley J Sheares; Elisa J Vincent; Yunling Du; Hossein Sadeghi; Moshe J Levison; Robert B Mellins; David Evans
Journal:  Am J Respir Crit Care Med       Date:  2010-12-07       Impact factor: 21.405

5.  Patterns of inhaled antiinflammatory medication use in young underserved children with asthma.

Authors:  Arlene M Butz; Mona Tsoukleris; Michele Donithan; Van Doren Hsu; Kim Mudd; Ilene H Zuckerman; Mary E Bollinger
Journal:  Pediatrics       Date:  2006-12       Impact factor: 7.124

6.  Better breathing or better living? A qualitative analysis of the impact of asthma medication acquisition on standard of living and quality of life in low-income families of children with asthma.

Authors:  Wendy J Ungar; Tony Macdonald; Martha Cousins
Journal:  J Pediatr Health Care       Date:  2005 Nov-Dec       Impact factor: 1.812

7.  Identification of gaps in the diagnosis and treatment of childhood asthma using a community-based participatory research approach.

Authors:  Toby C Lewis; Thomas G Robins; Christine L M Joseph; Edith A Parker; Barbara A Israel; Zachary Rowe; Katherine K Edgren; Maria A Salinas; Michael E Martinez; Randall W Brown
Journal:  J Urban Health       Date:  2004-09       Impact factor: 3.671

8.  Drug utilisation profile in the Italian paediatric population.

Authors:  Antonio Clavenna; Alessandra Berti; Lucia Gualandi; Elisa Rossi; Marisa De Rosa; Maurizio Bonati
Journal:  Eur J Pediatr       Date:  2008-04-30       Impact factor: 3.183

9.  What drives prescribing of asthma medication to children? A multilevel population-based study.

Authors:  Mira G P Zuidgeest; Liset van Dijk; Peter Spreeuwenberg; Henriëtte A Smit; Bert Brunekreef; Hubertus G M Arets; Madelon Bracke; Hubert G M Leufkens
Journal:  Ann Fam Med       Date:  2009 Jan-Feb       Impact factor: 5.166

10.  Inappropriate use of anti-asthmatic drugs in the Italian paediatric population.

Authors:  Antonio Clavenna; Elisa Rossi; Alessandra Berti; Giorgio Pedrazzi; Marisa De Rosa; Maurizio Bonati
Journal:  Eur J Clin Pharmacol       Date:  2003-09-06       Impact factor: 2.953

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