Literature DB >> 10428641

Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens.

A Plancarte1, A Flisser, C G Gauci, M W Lightowlers.   

Abstract

Pigs were immunised with antigens derived from Taenia solium oncospheres or with a pool of three recombinant antigens from Taenia ovis, and subsequently challenged with T. solium eggs. The native oncosphere antigens induced 83% protection against viable, and 89% protection against the total number of cysticerci established following the challenge infection. Immunisation with the recombinant T. ovis antigens induced 93% protection against the establishment of viable cysticerci, and 74% protection against the total number of cysticerci. These results, and those achieved elsewhere with Taenia saginata and T. ovis, support the possibility of developing a practical vaccine to assist in the control of transmission of T. solium through pigs.

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Year:  1999        PMID: 10428641     DOI: 10.1016/s0020-7519(99)00021-1

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN: 0020-7519            Impact factor:   3.981


  18 in total

1.  Molecular and functional characterization of a Taenia adhesion gene family (TAF) encoding potential protective antigens of Taenia saginata oncospheres.

Authors:  Luis Miguel Gonzalez; Pedro Bonay; Laura Benitez; Elizabeth Ferrer; Leslie J S Harrison; R Michael E Parkhouse; Teresa Garate
Journal:  Parasitol Res       Date:  2006-10-18       Impact factor: 2.289

2.  The highly antigenic 53/25 kDa Taenia solium protein fraction with cathepsin-L like activity is present in the oncosphere/cysticercus and induces non-protective IgG antibodies in pigs.

Authors:  Mirko Zimic; Mónica Pajuelo; Robert H Gilman; Andrés H Gutiérrez; Luis D Rueda; Myra Flores; Nancy Chile; Manuela Verástegui; Armando Gonzalez; Héctor H García; Patricia Sheen
Journal:  Vet Immunol Immunopathol       Date:  2011-11-11       Impact factor: 2.046

3.  Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens.

Authors:  Ana Flisser; Charles G Gauci; André Zoli; Joel Martinez-Ocaña; Adriana Garza-Rodriguez; Jose Luis Dominguez-Alpizar; Pablo Maravilla; Rossana Rodriguez-Canul; Guillermina Avila; Laura Aguilar-Vega; Craig Kyngdon; Stanny Geerts; Marshall W Lightowlers
Journal:  Infect Immun       Date:  2004-09       Impact factor: 3.441

Review 4.  Taenia solium cysticercosis.

Authors:  Héctor H García; Armando E Gonzalez; Carlton A W Evans; Robert H Gilman
Journal:  Lancet       Date:  2003-08-16       Impact factor: 79.321

5.  Characterization of S3Pvac anti-cysticercosis vaccine components: implications for the development of an anti-cestodiasis vaccine.

Authors:  Dunia Rassy; Raúl J Bobes; Gabriela Rosas; Victor H Anaya; Klaus Brehm; Beatriz Hernández; Jacquelynne Cervantes; Saúl Pedraza; Julio Morales; Nelly Villalobos; Aline S de Aluja; Juan P Laclette; Caris M Nunes; Germano F Biondi; Gladis Fragoso; Marisela Hernández; Edda Sciutto
Journal:  PLoS One       Date:  2010-06-23       Impact factor: 3.240

6.  Protection against Asiatic Taenia solium induced by a recombinant 45W-4B protein.

Authors:  Xuenong Luo; Yadong Zheng; Junling Hou; Shaohua Zhang; Xuepeng Cai
Journal:  Clin Vaccine Immunol       Date:  2008-12-17

7.  Effective production and purification of the glycosylated TSOL18 antigen, which is protective against pig cysticercosis.

Authors:  Xuepeng Cai; Gailing Yuan; Yadong Zheng; Xuenong Luo; Shaohua Zhang; Juntao Ding; Zhizhong Jing; Chengping Lu
Journal:  Infect Immun       Date:  2007-12-10       Impact factor: 3.441

8.  Characterization of a novel Taenia solium oncosphere antigen.

Authors:  Holger Mayta; Kathy Hancock; Min Z Levine; Robert H Gilman; Marilú J Farfán; Manuela Verastegui; William S Lane; Hector H Garcia; Armando E Gonzalez; Victor C W Tsang
Journal:  Mol Biochem Parasitol       Date:  2007-08-01       Impact factor: 1.759

9.  TSOL18/HP6-Tsol, an immunogenic Taenia solium oncospheral adhesion protein and potential protective antigen.

Authors:  R Michael E Parkhouse; Pedro Bonay; Luis Miguel González; Elizabeth Ferrer; Teresa Gárate; Cruz M Aguilar; Milagros M Cortez A; Leslie J S Harrison
Journal:  Parasitol Res       Date:  2008-01-24       Impact factor: 2.289

Review 10.  Human cysticercosis and Indian scenario: a review.

Authors:  Kashi Nath Prasad; Amit Prasad; Avantika Verma; Aloukick Kumar Singh
Journal:  J Biosci       Date:  2008-11       Impact factor: 1.826

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