Literature DB >> 10428266

Medication compliance following renal transplantation.

L R Raiz1, K M Kilty, M L Henry, R M Ferguson.   

Abstract

BACKGROUND: There appears to be general consensus that a relationship exists between noncompliance and clinical outcomes in health care, including renal transplantation. This study investigated variables associated with medication noncompliance after renal transplantation.
METHODS: A mail survey containing objective and subjective variables was sent to individuals who met eligibility criteria. Medication compliance was measured by two items: 1) Frequency of forgetting to take medications and 2) Frequency of not taking medications exactly as prescribed. Descriptive and multivariate analyses were utilized to examine the data.
RESULTS: Individuals who were older and those who perceived less pain were less likely to forget medications. The belief that health outcomes were controlled by chance and feeling bothered by part of the transplant experience were associated with greater likelihood of forgetting medications. Individuals who perceived a higher level of social functioning and those who believed that health outcomes were controlled by powerful others were more likely to take medications exactly as prescribed. An internal locus of control for health outcomes and feeling bothered by part of the transplant experience were associated with less likelihood of taking medication exactly as prescribed.
CONCLUSIONS: The finding of this study suggest that compliance with medications after renal transplant is associated with subjective, not objective variables. Positive feelings regarding their physicians and the transplant experience increased compliance. Combining consistent measurement of compliance, examination of its relationship to clinical outcomes, and appreciation for the patient perspective should result in increased levels of compliance and better clinical outcomes.

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Year:  1999        PMID: 10428266     DOI: 10.1097/00007890-199907150-00010

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  22 in total

Review 1.  Issues of adherence to immunosuppressant therapy after solid-organ transplantation.

Authors:  Marie A Chisholm
Journal:  Drugs       Date:  2002       Impact factor: 9.546

2.  Can focusing on self-care reduce disparities in kidney transplantation outcomes?

Authors:  Elisa J Gordon; Thomas Prohaska; Laura A Siminoff; Peter J Minich; Ashwini R Sehgal
Journal:  Am J Kidney Dis       Date:  2005-05       Impact factor: 8.860

3.  Noncompliance in the use of cardiovascular medications in the Medicare Part D population.

Authors:  Steven A Blackwell; David K Baugh; Melissa A Montgomery; Gary M Ciborowski; Charles J Waldron; Gerald F Riley
Journal:  Medicare Medicaid Res Rev       Date:  2011-12-14

Review 4.  Monitoring drug adherence.

Authors:  Sarah R Lieber; Jacqueline Helcer; Eyal Shemesh
Journal:  Transplant Rev (Orlando)       Date:  2015-04       Impact factor: 3.943

5.  The economic implications of non-adherence after renal transplantation.

Authors:  Irina Cleemput; Katrien Kesteloot; Yves Vanrenterghem; Sabina De Geest
Journal:  Pharmacoeconomics       Date:  2004       Impact factor: 4.981

6.  Time-in-a-bottle (TIAB): a longitudinal, correlational study of patterns, potential predictors, and outcomes of immunosuppressive medication adherence in adult kidney transplant recipients.

Authors:  Cynthia L Russell; Catherine Ashbaugh; Leanne Peace; Muammer Cetingok; Karen Q Hamburger; Sarah Owens; Deanna Coffey; Andrew W Webb; Donna Hathaway; Rebecca P Winsett; Richard Madsen; Mark R Wakefield
Journal:  Clin Transplant       Date:  2013 Sep-Oct       Impact factor: 2.863

7.  Selective retransplant after graft loss to nonadherence: success with a second chance.

Authors:  T B Dunn; B J Browne; K J Gillingham; R Kandaswamy; A Humar; W D Payne; D E R Sutherland; A J Matas
Journal:  Am J Transplant       Date:  2009-05-13       Impact factor: 8.086

8.  Adherence to immunosuppression: a prospective diary study.

Authors:  E J Gordon; T R Prohaska; M P Gallant; L A Siminoff
Journal:  Transplant Proc       Date:  2007-12       Impact factor: 1.066

Review 9.  Medication noncompliance and its implications in transplant recipients.

Authors:  Paul E Morrissey; Michelle L Flynn; Sonia Lin
Journal:  Drugs       Date:  2007       Impact factor: 9.546

10.  Medication adherence among heart and/or lung transplant recipients: An exploratory study.

Authors:  Rebecca A O'Brien; Parisa Aslani; Maria A Ciccia; Jo-Anne E Brien
Journal:  Patient Prefer Adherence       Date:  2008-02-02       Impact factor: 2.711

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