BACKGROUND: Hepatitis E virus (HEV) infection causes an acute, self-limited hepatitis associated with high mortality in pregnant women. Community-based surveys are scarce and information on HEV infection in populations is needed. The aim of this work was to study seroprevalence to HEV in young adults and children in Mexico, using a community-based survey. METHODS: Serum samples from 3,549 individuals were studied; the population included subjects from 1 to 29 years old from all regions of the country representing all socioeconomic levels. IgG anti-HEV was determined by ELISA. RESULTS: Anti-HEV antibodies were found in 374 (10.5%) individuals. Seroprevalence increased with age from 1.1% in children younger than 5 years to 14.2% in persons 26 to 29 years of age (p = 0.006). Risk factors for infection included living in rural communities and a low educational level. Seroprevalence was not associated with the level of regional development. CONCLUSIONS: HEV infection is endemic in Mexico. Age, type of community, and educational level were identified as risk factors for infection.
BACKGROUND:Hepatitis E virus (HEV) infection causes an acute, self-limited hepatitis associated with high mortality in pregnant women. Community-based surveys are scarce and information on HEVinfection in populations is needed. The aim of this work was to study seroprevalence to HEV in young adults and children in Mexico, using a community-based survey. METHODS: Serum samples from 3,549 individuals were studied; the population included subjects from 1 to 29 years old from all regions of the country representing all socioeconomic levels. IgG anti-HEV was determined by ELISA. RESULTS: Anti-HEV antibodies were found in 374 (10.5%) individuals. Seroprevalence increased with age from 1.1% in children younger than 5 years to 14.2% in persons 26 to 29 years of age (p = 0.006). Risk factors for infection included living in rural communities and a low educational level. Seroprevalence was not associated with the level of regional development. CONCLUSIONS:HEVinfection is endemic in Mexico. Age, type of community, and educational level were identified as risk factors for infection.
Authors: Montserrat Elemi García-Hernández; Mayra Cruz-Rivera; José Iván Sánchez-Betancourt; Oscar Rico-Chávez; Arely Vergara-Castañeda; María E Trujillo; Rosa Elena Sarmiento-Silva Journal: BMC Vet Res Date: 2017-09-21 Impact factor: 2.741
Authors: Cosme Alvarado-Esquivel; Ada Agustina Sandoval-Carrillo; José Manuel Salas-Pacheco; Elizabeth Irasema Antuna-Salcido; Karla Sujey Castro-Martínez; Diana Stephanie Ortiz-Montaño; Isabel Beristain-Garcia; Agar Ramos-Nevarez; Antonio Sifuentes-Alvarez; Elizabeth Rábago-Sánchez; Sandra Margarita Cerrillo-Soto; Edith Contreras-Cisneros Journal: Iran J Public Health Date: 2021-01 Impact factor: 1.429