Literature DB >> 10427875

Cervical cancer screening in developing countries: why is it ineffective? The case of Mexico.

E C Lazcano-Ponce1, S Moss, P Alonso de Ruíz, J Salmerón Castro, M Hernández Avila.   

Abstract

BACKGROUND: Mexico established a national cervical cancer-screening program in 1974. Despite the implementation of the program, there was a steady mortality trend of 16 per 100,000 women over 15 years.
METHODS: A diagnostic procedure of the pitfalls was applied to the following steps of the screening procedure: Pap sampling quality; cytological diagnosis validity; compliance of women; and determinants of non-participation.
RESULTS: The low effectiveness of screening on cervical cancer is principally due to factors associated with quality and coverage. Pap quality is deficient; 64% of a random sample of specimens lacked endocervical cells. Reading centers presented false negative indices of between 10 and 54%. Women seek screening in a late stage of disease (55% with cervical cancer seek care because they have symptoms). In addition, coverage is low; in women between 15 and 49 years of age in Mexico City, 64.2% have a history of Pap, compared with 30% in rural areas. Knowledge of what the Pap is used for strongly determines the use of screening. In rural areas, only 40% of women are informed about the purpose of the Pap test.
CONCLUSIONS: A proposal to reorganize Mexico's screening program includes the following five main strategies: (a) increased coverage; (b) improved quality control of how cervical smears are taken; (c) better interpretation of Pap tests; (d) guaranteed treatment for those whose tests show abnormalities, and (e) improved follow-up.

Entities:  

Mesh:

Year:  1999        PMID: 10427875     DOI: 10.1016/s0188-0128(99)00006-8

Source DB:  PubMed          Journal:  Arch Med Res        ISSN: 0188-4409            Impact factor:   2.235


  23 in total

1.  Cervical cancer in the developing world.

Authors:  J Sherris; C Herdman; C Elias
Journal:  West J Med       Date:  2001-10

2.  Clinician offering is a key factor associated with HPV vaccine uptake among Mexican mothers in the USA and Mexico: a cross-sectional study.

Authors:  Yvonne N Flores; Jorge Salmerón; Beth A Glenn; Cathy M Lang; L Cindy Chang; Roshan Bastani
Journal:  Int J Public Health       Date:  2018-12-01       Impact factor: 3.380

3.  Maternal support for human papillomavirus vaccination in Honduras.

Authors:  Rebecca B Perkins; Sarah M Langrish; Deborah J Cotton; Carol J Simon
Journal:  J Womens Health (Larchmt)       Date:  2010-11-22       Impact factor: 2.681

4.  Immigration, health care access, and recent cancer tests among Mexican-Americans in California.

Authors:  Nancy Breen; Sowmya R Rao; Helen I Meissner
Journal:  J Immigr Minor Health       Date:  2010-08

5.  Knowledge, Awareness and Prevention of Cervical Cancer among Women Attending a Tertiary Care Hospital in Puducherry, India.

Authors:  Jansirani Siddharthar; Bhuvaneshwari Rajkumar; Kuberan Deivasigamani
Journal:  J Clin Diagn Res       Date:  2014-06-20

6.  Mexican physicians' knowledge and attitudes about the human papillomavirus and cervical cancer: a national survey.

Authors:  T Aldrich; D Becker; S G García; D Lara
Journal:  Sex Transm Infect       Date:  2005-04       Impact factor: 3.519

7.  Impact of patient adherence and test performance on the cost-effectiveness of cervical cancer screening in developing countries: the case of Honduras.

Authors:  Rebecca B Perkins; Sarah M Langrish; Linda J Stern; James F Burgess; Carol J Simon
Journal:  Womens Health Issues       Date:  2009-11-26

8.  A population-based study of visual inspection with acetic acid (VIA) for cervical screening in rural Nigeria.

Authors:  Kayode Olusegun Ajenifuja; Julia C Gage; Akinfolarin C Adepiti; Nicolas Wentzensen; Claire Eklund; Mary Reilly; Martha Hutchinson; Robert D Burk; Mark Schiffman
Journal:  Int J Gynecol Cancer       Date:  2013-03       Impact factor: 3.437

9.  ELISA test to detect CDKN2A (p16(INK4a)) expression in exfoliative cells: a new screening tool for cervical cancer.

Authors:  Li Ding; Xian-Jin Zou; Jin-E Ao; Ai-Xiang Yao; Lan Cai
Journal:  Mol Diagn Ther       Date:  2008       Impact factor: 4.074

10.  Socioeconomic determinants of cervical cancer screening in Latin America.

Authors:  Samir Soneji; Natsu Fukui
Journal:  Rev Panam Salud Publica       Date:  2013-03
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