Literature DB >> 10426942

Src autoinhibition: let us count the ways.

S R Hubbard.   

Abstract

Src family tyrosine kinases are key cellular signaling enzymes whose catalytic activities are tightly controlled. Recent structural and mutational studies have revealed additional intricacies in the autoinhibitory mechanisms by which catalytic activity is repressed.

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Year:  1999        PMID： 10426942     DOI： 10.1038/11468

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  22 in total

1.  SRC family kinases and receptors: analysis of three activation mechanisms by dynamic systems modeling.

Authors:  Hendrik Fuss; Werner Dubitzky; C Stephen Downes; Mary Jo Kurth
Journal:  Biophys J       Date:  2007-11-30       Impact factor: 4.033

2.  Biochemistry on a leash: the roles of tether length and geometry in signal integration proteins.

Authors:  David Van Valen; Mikko Haataja; Rob Phillips
Journal:  Biophys J       Date:  2009-02-18       Impact factor: 4.033

3.  An electrostatic network and long-range regulation of Src kinases.

Authors:  Elif Ozkirimli; Shalini S Yadav; W Todd Miller; Carol Beth Post
Journal:  Protein Sci       Date:  2008-08-07       Impact factor: 6.725

4.  Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension.

Authors:  Wai K P Wong; James A Knowles; Jane H Morse
Journal:  Am J Respir Cell Mol Biol       Date:  2005-07-07       Impact factor: 6.914

5.  Phosphorylation-dependent and phosphorylation-independent modes of modulation of shaker family voltage-gated potassium channels by SRC family protein tyrosine kinases.

Authors:  Michael N Nitabach; D Alberto Llamas; Ian J Thompson; Kerry A Collins; Todd C Holmes
Journal:  J Neurosci       Date:  2002-09-15       Impact factor: 6.167

6.  Regulation of the Src family kinase Lck by Hsp90 and ubiquitination.

Authors:  Ana Giannini; Marie-José Bijlmakers
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

7.  Proline cis-trans isomerization controls autoinhibition of a signaling protein.

Authors:  Paramita Sarkar; Charles Reichman; Tamjeed Saleh; Raymond B Birge; Charalampos G Kalodimos
Journal:  Mol Cell       Date:  2007-02-09       Impact factor: 17.970

8.  The carboxyl terminus controls ligand-dependent activation of VEGFR-2 and its signaling.

Authors:  Rosana D Meyer; Amrik J Singh; Nader Rahimi
Journal:  J Biol Chem       Date:  2003-10-21       Impact factor: 5.157

9.  Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Authors:  Amanda Oldani; Mireille Cormont; Veronique Hofman; Valentina Chiozzi; Olivier Oregioni; Alexandra Canonici; Anna Sciullo; Patrizia Sommi; Alessia Fabbri; Vittorio Ricci; Patrice Boquet
Journal:  PLoS Pathog       Date:  2009-10-02       Impact factor: 6.823

10.  The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells.

Authors:  Yoshihisa Kaizuka; Adam D Douglass; Santosh Vardhana; Michael L Dustin; Ronald D Vale
Journal:  J Cell Biol       Date:  2009-04-27       Impact factor: 10.539
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