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Literature DB >> 10426400

Programmed cell death in the terminal endbud.

Abstract

Ductal development in the pubertal mouse mammary gland is characterized by dramatic morphological changes in the epithelium driven by proliferation of cap and body cells in the terminal endbuds. Recent experiments revealed a coincident and abundant apoptosis in the body cells of these structures. The cells undergoing apoptosis are occasionally restricted to defined regions within the terminal endbud. Localization adjacent to the presumptive lumina suggests that this process functions to sculpt the lumina of the subtending duct. Members of the Bcl-2 family of apoptosis regulatory molecules; Bcl-2 and Bcl-x, appear to have some role in regulating apoptosis in the terminal endbud. Other possible signals which could regulate this developmental process and a model are presented.

Entities: Gene Species

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Year: 1999 PMID： 10426400 DOI： 10.1023/a:1018733426625

Source DB: PubMed Journal: J Mammary Gland Biol Neoplasia ISSN： 1083-3021 Impact factor: 2.673

45 in total

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12 in total

Review 1. Establishing a framework for the functional mammary gland: from endocrinology to morphology.

Authors: Russell C Hovey; Josephine F Trott; Barbara K Vonderhaar
Journal: J Mammary Gland Biol Neoplasia Date: 2002-01 Impact factor: 2.673

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Authors: Lisa M Coussens; Jeffrey W Pollard
Journal: Cold Spring Harb Perspect Biol Date: 2011-03-01 Impact factor: 10.005

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Authors: D J Flint; E Tonner; J Beattie; G J Allan
Journal: J Mammary Gland Biol Neoplasia Date: 2008-11-08 Impact factor: 2.673

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Journal: J Mammary Gland Biol Neoplasia Date: 1999-04 Impact factor: 2.673

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Journal: J Mammary Gland Biol Neoplasia Date: 2000-01 Impact factor: 2.673

6. Mfge8 is critical for mammary gland remodeling during involution.

Authors: Kamran Atabai; Rafael Fernandez; Xiaozhu Huang; Iris Ueki; Ahnika Kline; Yong Li; Sepid Sadatmansoori; Christine Smith-Steinhart; Weimin Zhu; Robert Pytela; Zena Werb; Dean Sheppard
Journal: Mol Biol Cell Date: 2005-09-29 Impact factor: 4.138

Review 7. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.

Authors: David L Kleinberg; Teresa L Wood; Priscilla A Furth; Adrian V Lee
Journal: Endocr Rev Date: 2008-12-15 Impact factor: 19.871

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Authors: David L Kleinberg; Weifeng Ruan
Journal: J Mammary Gland Biol Neoplasia Date: 2008-11-25 Impact factor: 2.673

9. Expression of NR5A2, NUP153, HNF4A, USP15 and FNDC3B is consistent with their use as novel biomarkers for bovine mammary stem/progenitor cells.

Authors: Ratan K Choudhary; Anthony V Capuco
Journal: J Mol Histol Date: 2021-01-05 Impact factor: 2.611

10. Loss of protein kinase C delta alters mammary gland development and apoptosis.

Authors: B L Allen-Petersen; M R Miller; M C Neville; S M Anderson; K I Nakayama; M E Reyland
Journal: Cell Death Dis Date: 2010 Impact factor: 8.469