R Matijevic1, T Johnston. 1. University of Manchester Department of Obstetrics and Gynaecology, St. Mary's Hospital, Whitworth Park.
Abstract
OBJECTIVE: To assess the ability of colour/pulsed Doppler ultrasound to detect failed physiologic change of the spiral arteries in pregnancies complicated by pre-eclampsia. DESIGN: Prospective matched-pairs case controlled study. SETTING: Tertiary referral teaching hospital. SAMPLE: Sixteen women with severe pre-eclampsia and 16 normotensive controls. METHODS: Colour/pulsed Doppler assessment of blood flow in the uterine arteries and spiral arteries in central and peripheral parts of the placental bed. MAIN OUTCOME MEASURES: Impedance to blood flow in the spiral arteries in pre-eclamptic group compared with normotensive controls. RESULTS: In women with pre-eclampsia there is significantly higher impedance to blood flow in spiral arteries compared with normotensive women. CONCLUSIONS: Ultrasound colour/pulsed Doppler based investigation of blood flow in the spiral arteries in ongoing pregnancy can detect failed physiological change of these vessels in pre-eclampsia. This is in concordance with histologic data.
OBJECTIVE: To assess the ability of colour/pulsed Doppler ultrasound to detect failed physiologic change of the spiral arteries in pregnancies complicated by pre-eclampsia. DESIGN: Prospective matched-pairs case controlled study. SETTING: Tertiary referral teaching hospital. SAMPLE: Sixteen women with severe pre-eclampsia and 16 normotensive controls. METHODS: Colour/pulsed Doppler assessment of blood flow in the uterine arteries and spiral arteries in central and peripheral parts of the placental bed. MAIN OUTCOME MEASURES: Impedance to blood flow in the spiral arteries in pre-eclamptic group compared with normotensive controls. RESULTS: In women with pre-eclampsia there is significantly higher impedance to blood flow in spiral arteries compared with normotensive women. CONCLUSIONS: Ultrasound colour/pulsed Doppler based investigation of blood flow in the spiral arteries in ongoing pregnancy can detect failed physiological change of these vessels in pre-eclampsia. This is in concordance with histologic data.
Authors: Alexander Weichert; Andreas Hagen; Michael Tchirikov; Ilka B Fuchs; Wolfgang Henrich; Michael Entezami Journal: Geburtshilfe Frauenheilkd Date: 2017-05-24 Impact factor: 2.915
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