| Literature DB >> 10425302 |
Y Hida1, T Morita, M Fujita, Y Miyasaka, S Horita, Y Fujioka, K Nagashima, H Katoh.
Abstract
Hepatocyte growth factor (HGF)/c-Met expression is known to be correlated with poor prognosis in several cancers. We investigated HGF/c-Met immunoreactivity and its correlation with clinical features in 51 patients with curatively resected extrahepatic biliary tract carcinoma. c-Met showed significant correlations with tumor location, T category, stage, perineural invasion and local recurrence. Overall survival in patients with HGF and c-Met immunopositivity was significantly worse than in those who were negative. Our findings suggest that HGF/c-Met play some roles in tumor development and that HGF/c-Met immunoreactivity could be a predictor of the mode of recurrence and poor prognosis.Entities:
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Year: 1999 PMID： 10425302 DOI： 10.3892/or.6.5.1051
Source DB: PubMed Journal: Oncol Rep ISSN： 1021-335X Impact factor: 3.906