Literature DB >> 10425135

A cytotoxic triterpene saponin from the root bark of Aralia dasyphylla.

K Xiao1, Y H Yi, Z Z Wang, H F Tang, Y Q Li, H W Lin.   

Abstract

A novel triterpene saponin (1) was isolated from an ethanol extract of the root bark of Aralia dasyphylla. Its structure was elucidated as 3-O-[beta-D-glucopyranosyl (1-->3)-beta-D-galactopyranosyl(1-->2)]-beta-D-glucuronopyranosyl- ole anolic acid-28-O-beta-D-glucopyranoside, according to spectral and chemical evidence. Compound 1 showed significant cytotoxic activity against KB and Hela-S(3) cells.

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Year:  1999        PMID： 10425135     DOI： 10.1021/np9805185

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

1.  Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational approach.

Authors:  Ziyad Tariq Muhseen; Alaa R Hameed; Halah M H Al-Hasani; Muhammad Tahir Ul Qamar; Guanglin Li
Journal:  J Mol Liq       Date:  2020-10-07       Impact factor: 6.165

2.  The influence of LTS-4, a saponoside from Lysimachia thyrsiflora L., on human skin fibroblasts and human melanoma cells.

Authors:  Agnieszka Galanty; Marta Michalik; Lukasz Sedek; Irma Podolak
Journal:  Cell Mol Biol Lett       Date:  2008-06-13       Impact factor: 5.787
  2 in total

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