Literature DB >> 10421571

Kinase phosphorylation: Keeping it all in the family.

R T Peterson1, S L Schreiber.   

Abstract

The identification of PDK1 as a kinase that phosphorylates the AGC family of kinases led to a hunt for 'PDK2', a hypothetical regulated kinase(s) that would be required for full activation of the AGC kinases. Recent findings suggest that the elusive PDK2 may actually be a familiar kinase with an atypical associate.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10421571     DOI： 10.1016/s0960-9822(99)80326-1

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  32 in total

1.  Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesis.

Authors:  Andrea Bimbó; Jianhua Liu; Mohan K Balasubramanian
Journal:  Mol Biol Cell       Date:  2005-04-27       Impact factor: 4.138

2.  The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module.

Authors:  Natarajan Kannan; Nina Haste; Susan S Taylor; Andrew F Neuwald
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-16       Impact factor: 11.205

3.  In vivo activation of protein kinase A in Schizosaccharomyces pombe requires threonine phosphorylation at its activation loop and is dependent on PDK1.

Authors:  Yi Tang; Maureen McLeod
Journal:  Genetics       Date:  2004-12       Impact factor: 4.562

4.  Kinetic mechanism of fully activated S6K1 protein kinase.

Authors:  Malik M Keshwani; Thomas K Harris
Journal:  J Biol Chem       Date:  2008-03-06       Impact factor: 5.157

5.  Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.

Authors:  Paramita Mookherjee; Rodrigo Quintanilla; Myoung-Sun Roh; Anna A Zmijewska; Richard S Jope; Gail V W Johnson
Journal:  J Cell Biochem       Date:  2007-09-01       Impact factor: 4.429

6.  Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII).

Authors:  Malik M Keshwani; Duncan B Ross; Timothy J Ragan; Thomas K Harris
Journal:  Protein Expr Purif       Date:  2007-11-19       Impact factor: 1.650

7.  PDK1 regulates growth through Akt and S6K in Drosophila.

Authors:  F Rintelen; H Stocker; G Thomas; E Hafen
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

8.  Steady-state kinetic mechanism of PDK1.

Authors:  Xinxin Gao; Thomas K Harris
Journal:  J Biol Chem       Date:  2006-05-31       Impact factor: 5.157

9.  Characterization of the mechanisms controlling Greatwall activity.

Authors:  Suzanne Vigneron; Aicha Gharbi-Ayachi; Anne-Aurélie Raymond; Andrew Burgess; Jean-Claude Labbé; Gilles Labesse; Bernard Monsarrat; Thierry Lorca; Anna Castro
Journal:  Mol Cell Biol       Date:  2011-03-28       Impact factor: 4.272

10.  Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1).

Authors:  Timothy J Ragan; Duncan B Ross; Malik M Keshwani; Thomas K Harris
Journal:  Protein Expr Purif       Date:  2007-10-01       Impact factor: 1.650
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.