Literature DB >> 10421164

Technique for heterotopic pig heart xenotransplantation in primates.

D H Adams1, R H Chen, A Kadner, S Naficy.   

Abstract

The primate is a commonly utilized model for the human immune response after heart transplantation. This report describes our experience with heterotopic abdominal transplantation of porcine hearts into primate recipients. Abdominal graft placement was surprisingly well tolerated, and we found this approach to be particularly useful in the setting of significant donor-recipient size mismatch. Continuous monitoring with an implantable monitoring system facilitated assessment of graft viability in awake recipients; progressive graft bradycardia and decreasing QRS amplitude were predictive of ensuing graft failure.

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Year:  1999        PMID： 10421164     DOI： 10.1016/s0003-4975(99)00488-9

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN： 0003-4975            Impact factor:   4.330


  8 in total

1.  B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months.

Authors:  M M Mohiuddin; P C Corcoran; A K Singh; A Azimzadeh; R F Hoyt; M L Thomas; M A Eckhaus; C Seavey; D Ayares; R N Pierson; K A Horvath
Journal:  Am J Transplant       Date:  2011-11-09       Impact factor: 8.086

2.  Rejection severity directly correlates with myocyte apoptosis in pig-to-baboon cardiac xenotransplantation.

Authors:  Joel G R Weaver; Christopher G A McGregor; Henry D Tazelaar; Andrew D Badley
Journal:  J Heart Lung Transplant       Date:  2005-07       Impact factor: 10.247

3.  Anaesthetic management of baboons undergoing heterotopic porcine cardiac xenotransplantation.

Authors:  D Santerre; R H Chen; A Kadner; D Lee-Parritz; D H Adams
Journal:  Vet Res Commun       Date:  2001-05       Impact factor: 2.459

Review 4.  The complex functioning of the complement system in xenotransplantation.

Authors:  Hongmin Zhou; Hidetaka Hara; David K C Cooper
Journal:  Xenotransplantation       Date:  2019-04-29       Impact factor: 3.907

5.  Left ventricular pressure measurement by telemetry is an effective means to evaluate transplanted heart function in experimental heterotopic cardiac xenotransplantation.

Authors:  K A Horvath; P C Corcoran; A K Singh; R F Hoyt; C Carrier; M L Thomas; M M Mohiuddin
Journal:  Transplant Proc       Date:  2010 Jul-Aug       Impact factor: 1.066

6.  Surgical and nonsurgical complications of a pig to baboon heterotopic heart transplantation model.

Authors:  P C Corcoran; K A Horvath; A K Singh; R F Hoyt; M L Thomas; M A Eckhaus; M M Mohiuddin
Journal:  Transplant Proc       Date:  2010 Jul-Aug       Impact factor: 1.066

7.  Intra-Abdominal Heterotopic Cardiac Xenotransplantation: Pearls and Pitfalls.

Authors:  Laura DiChiacchio; Avneesh K Singh; Joshua L Chan; Nicole M Shockcor; Tianshu Zhang; Billeta G Lewis; David Ayares; Philip Corcoran; Keith A Horvath; Muhammad M Mohiuddin
Journal:  Front Cardiovasc Med       Date:  2019-07-25

Review 8.  Aspects of the Complement System in New Era of Xenotransplantation.

Authors:  Shuji Miyagawa; Akira Maeda; Chiyoshi Toyama; Shuhei Kogata; Chizu Okamatsu; Riho Yamamoto; Kazunori Masahata; Masafumi Kamiyama; Hiroshi Eguchi; Masahito Watanabe; Hiroshi Nagashima; Masahito Ikawa; Katsuyoshi Matsunami; Hiroomi Okuyama
Journal:  Front Immunol       Date:  2022-04-14       Impact factor: 8.786
  8 in total

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